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Email:: ap1s07@soton.ac.uk

Dr Alexandra J Kermack MBBS, PhD, MRCOG

NIHR Clinical Lecturer in Obstetrics and Gynaecology, Specialist Registrar,Module Lead for the Endocrine and Lifecycle Module, year 2 of the BM programme

Dr Alexandra Kermack is an NIHR Clinical Lecturer of Obstetrics and Gynaecology within Medicine at the University of Southampton

Interested in the effect of lifestyle and nutrition on the developing embryo and women’s health

My research examines the effect of lifestyle, specifically diet, on fertility and pregnancy outcomes. I am interested in studying the periconceptual period of time as an opportunity to alter the health of mothers and their offspring. My research to date has had an emphasis on the effect of omega 3 on embryo development.

Qualifications

BSc (1st), Orthopaedic Science, University College London, 2005
MBBS (11th centile), Medicine and Surgery, Kings College London, 2008
PhD (pass), Medicine, University of Southampton, 2019
MRCOG (pass), Obstetrics and Gynaecology, RCOG, 2019

Appointments held

NIHR Clinical Lecturer in Obstetrics and Gynaecology 2019 – date
Module Lead for the Endocrine and Lifecycle Module (BM Year 2 medicine programme) 2019 – date

Research

Publications

Teaching

Contact

I am interested in the effects of lifestyle and nutrition on fertility and pregnancy outcomes

PREPARE - A randomised controlled trial of a preconceptional dietary intervention in women undergoing IVF treatment.

PROMOTE - A prospective randomised trial comparing embryo development in the standard benchtop incubator versus the time lapse system

WRIST – Wellbeing and resilience in specialist trainees, a study examining the impact of a mentoring scheme on trainees in obstetrics and gynaecology

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Articles

Kermack, A., Lowen , P., Wellstead , S. J., Fisk, H., Montag, M., Cheong, Y., Osmond, C., Houghton, F. D., Calder, P., & Macklon, N. (2020). Effect of a 6-week “Mediterranean” dietary intervention on in vitro human embryo development: the Preconception Dietary Supplements in Assisted Reproduction double-blinded randomized controlled trial. Fertility and Sterility, 113(2), 260-269. https://doi.org/10.1016/j.fertnstert.2019.09.041
Kermack, A. J., Finn-Sell, S., Cheong, Y. C., Brook, N., Eckert, J. J., Macklon, N. S., & Houghton, F. D. (2015). Amino acid composition of human uterine fluid: association with age, lifestyle and gynaecological pathology. Human Reproduction, 30(4), 917-924. https://doi.org/10.1093/humrep/dev008
Kermack, A. J., & Macklon, N. S. (2015). Nutritional supplementation and artificial reproductive technique (ART) outcomes. Reproduction, Fertility and Development, 27(4), 677-683. https://doi.org/10.1071/RD14304
Kermack, A., van Rijn, B., Houghton, F. D., Calder, P., Cameron, I. T., & Macklon, N. (2015). The ‘Developmental Origins’ hypothesis: relevance to the obstetrician and gynecologist. Journal of Developmental Origins of Health and Disease, 6(5), 415-424. https://doi.org/10.1017/S2040174415001324
Kermack, A. J., Calder, P. C., Houghton, F. D., Godfrey, K. M., & Macklon, N. S. (2014). A randomised controlled trial of a preconceptional dietary intervention in women undergoing IVF treatment (PREPARE trial). BMC Women’s Health, 14, [130]. https://doi.org/10.1186/1472-6874-14-130
Kermack, A. J., & Macklon, N. S. (2013). Preconception care and fertility. Minerva Ginecologica, 65(3), 253-269. http://www.minervamedica.it/en/journals/minerva-ginecologica/article.php?cod=R09Y2013N03A0253

Module Lead of the Endocrine and Lifecycle module in Year 2 of the BM programme

Lecturer in Obstetrics and Gynaecology module in Year 4 of the BM programme

Dr Alexandra J Kermack
Princess Anne Hospital
Mailpoint 815, Level F
Coxford Road, Southampton
SO16 5YA, UK

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