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Centre for Human Development, Stem Cells and Regeneration

Image of a mouse pancreatic organoid, nuclei are labelled in green or purple dependent on cell proliferation status

The CHDSCR brings together researchers studying stem cells and development and ways to promote the regeneration of diseased or injured tissues. We aim to provide an environment where excellent scientists can make exciting discoveries for patient benefit.

Part of Medicine

About

Our Vision: Translating pioneering developmental and stem cell science for patient benefit.

The Centre for Human Development, Stem Cells and Regeneration (CHDSCR) was founded in 2004 as a cross-disciplinary research and translational programme within the Faculty of Medicine at the University of Southampton.

The Centre undertakes fundamental research into early development and stem cells together with applied translational research targeting the NHS and patient benefit.

The Centre has vibrant and thriving interdisciplinary research programmes that harness the translational strength of the University together with an MRes program in Stem Cells, outstanding clinical infrastructure and enterprise to deliver on this vision.

The Centre comprises a grouping of scientists and clinician scientists with a shared interest in Stem Cells, Development and Regenerative Medicine within excellent core space in the Institute of Developmental Sciences and units across Southampton General Hospital and Institute for Life Sciences

Our Mission: Our aim is to understand early human development and fundamental stem cell biology to inform and aid our translation and development of cell therapies for regenerative medicine.

Professor Jon Dawson - Director

Research highlights

An extreme close-up of the tip of an injection needle, with a drop of nanoclay sitting at the tip.

Using nanoclay gel to regrow, repair and replace damaged cells

Health and wellbeing
Southampton researchers have developed an innovative medical clay that can be used to apply regenerative medicine to patients with musculoskeletal conditions.

People, projects, publications and PhDs

People

Dr Angus Wann PhD

Associate Professor in Cell Physiology

Research interests

  • A core interest in the group is molecular, cellular, tissue and organ level mechanobiology. This is often studied through the lens of primary cilia biology. We are developing developmental engineering approaches to tissue biology which also help us to study the relevance of our discovery science in the realms of chondropathies e.g Osteoarthritis and chondrodysplasia.  We have interests in matrix turnover in development and disease and maturation of matrices to support life-long health of tissues.  Finally, we have a long-standing interest in the Intergration of mechanobiology and inflammation through the genes and proteins associated with primary cilia or ciliome. 

Accepting applications from PhD students

Email: a.k.t.wann@soton.ac.uk

Address: B85, East Highfield Campus, University Road, SO17 1BJ (View in Google Maps)

ORCID

Professor Jaswinder Sethi BSc DPhil FRSB

Professor of Immunometabolism

Research interests

  • Immunometabolism
  • Obesity
  • Metabolic diseases

Accepting applications from PhD students

Email: j.sethi@soton.ac.uk

Address: Southampton General Hospital, Tremona Road Shirley, SO16 6YD (View in Google Maps)

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Professor Jon Dawson

Prof Fellow of Regenerative Medicine

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Enquiries

If you have specific research enquiries, please contact individual academics listed in the 'People' section on this page.

Centre for Human Development, Stem Cells and Regeneration
Faculty of Medicine (School of Human Development and Health) 
University of Southampton  
Southampton General Hospital 
Tremona Road
Southampton SO16 6YD

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