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The University of Southampton
Biological Sciences

Research project: Calcium ATPases - role in calcium homeostasis and signalling

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Calcium has many important functions within the cells of higher plants. It has structural roles, particularly in the composition of the cell wall, it is an enzyme cofactor, it is involved in the cellular secretory pathway, and it is an intracellular messenger, functioning in coupling different extracellular stimuli to many physiological responses.

Ca2+-ATPases catalyse the active efflux of calcium into the extracellular space or into internal stores such as the vacuole or endoplasmic reticulum, thereby maintaining low cytosolic calcium levels and allowing calcium to function as a signalling molecule. We are investigating the role of these transporters in plants in relation to calcium/divalent cation homeostasis and signalling.

Related research groups

Molecular and Cellular Biosciences
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