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The University of Southampton
Biological Sciences

Research project: Dissecting pathways involved in Manganese homeostasis and stress in higher plant cells

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Manganese (Mn) is an essential heavy metal micronutrient in plants having a range of cellular functions.

Manganese (Mn) homeostasis involves the coordinated operation of transporters mediating cellular import and export and distribution between cell organelles. These processes are required to ensure that Mn reaches its correct target proteins and also for cellular Mn detoxification. Significant progress has been made in identifying transport mechanisms in plants responsible for Mn uptake from the soil, distribution around the plant and compartmentalisation within the cell. Transporters that have been implicated in Mn transport include members of the P2A-type ATPase, ZIP, CAX, CDF, NRAMP and OPT/YSL families. This project is focussed on the role of transporters in the acquisition, distribution and homeostasis of Mn, and aspects of their regulation.

Related research groups

Molecular and Cellular Biosciences
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