Macrocyclic and Bio-inorganic Chemistry

Learning Outcomes

Learning Outcomes

Having successfully completed this module you will be able to:

• Demonstrate detailed appreciation of the challenges and solutions associated with the successful preparation of macrocycles with a range of donor atom types (O, N, S, Se, P) and their complexes, as well as developing the necessary skills in analysing and interpreting spectroscopic and analytical data on these systems, so that previously unseen examples and/or reaction schemes may be correctly identified and rationalised.
• Describe how metals can be utilised in medical applications from both a therapeutic and diagnostic perspective.
• Describe in detail how metal ions are important in biological processes and why the coordination environment around the metal centre plays a crucial role in its function.
• Demonstrate an appreciation of how and why macrocyclic ligands can support coordination of metal ions in unusual oxidation states, how to optimise these characteristics for particular metals and their development towards electrocatalysis.
• Be able to provide a sound basis for the macrocyclic effect in terms of both kinetic and thermodynamic considerations, and link this closely to the potential and actual applications of macrocyclic systems in a range of domains, including a detailed understanding of the key factors influencing the design of macrocyclic frameworks suitable for the selective extraction of particular metal ions (s-block, p-block and 1st row d-block).

Summative

This is how we’ll formally assess what you have learned in this module.

Referral

This is how we’ll assess you if you don’t meet the criteria to pass this module.