The natural history of asthma and allergy across the lifecourse.Identification of risk factors for asthma and allergy across the lifecourse.Development of risk prediction scores and new diagnostics for asthma.Prevention strategies for asthma and allergy.Phenotyping and endotypic understanding of difficult-to-treat asthma.T-cell biology of severe asthma.The role of micro-RNAs as diagnostic and prognostic biomarkers in asthma.Understanding the multimorbidity framework of difficult-to-treat asthma.Developing multimodal interventions for difficult-to-treat asthma.
1- Elucidation of mechanisms of disease resistance in Staphylococcus aureus-mediated chronic rhinosinusitis.
2- Use of the nose to develop novel biomarkers to enable early detection and monitoring of dementia (collaboration with the Carare Research Group).
3- Characterisation of the sinonasal microbiome and its diversity in adult Primary Ciliary Dyskinesia, and its impact on upper airway disease severity (collaboration with the PCD Group).
