Research project

Developing 2 & 3 dimensional models to improve treatment and diagnosis of osteosarcoma

Research groups:

Chemical Biology, Diagnostics and Therapeutics
Lead researcher:

Dr Claire Clarkin
Other researchers:

Professor Stephen Beers,

Dr Janos Kanczler,

Professor Sumeet Mahajan
Research funder:

Children with Cancer UK
Status:

Not active

Staff

Lead researcher

Dr Claire Clarkin

Assoc Prof in Develpmtl & Skeltl Biology

Email: c.e.clarkin@soton.ac.uk

Other researchers

Professor Stephen Beers

Professor of Immunology & Immunotherapy

Research interests

Edit
Antibody Effector Functions Monoclonal antibodies (mAb) have become established in the treatment of a variety of malignancies - transforming patient outcomes. Despite this undoubted impact, responses remain variable and their mechanisms of action and of tumour resistance are controversial. Our research is focussed on understanding these complex processes using a variety of complementary models and systems to better inform antibody selection, design and clinical application.
Current research interests:

Email: s.a.beers@soton.ac.uk

Dr Janos Kanczler

Lecturer

Email: j.kanczler@soton.ac.uk

Professor Sumeet Mahajan MSc, MTech, PhD, FHEA, FRSC

Prof of Molecular BioPhotonics & Imaging

Email: s.mahajan@soton.ac.uk

Collaborating research institutes, centres and groups

Cell and Developmental Biology

We explore how molecular interactions between proteins and small molecules, defined at atomic resolution, govern biochemical output and in turn control cell behaviour.

Chemical Biology, Diagnostics and Therapeutics

We investigate the properties of biomolecules – including an assortment of DNA, proteins, lipids and carbohydrates.