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Research project

Combining structural biology with AI-guided protein design to develop new antibody-degrading enzymes.

Staff

Lead researchers

Professor Max Crispin DPhil, FRSB, FRSC, FHEA

Director of Inst for Life Sciences
Research interests
  • Viral Glycobiology
  • Therapeutic Antibodies
Connect with Max

Email: Max.Crispin@soton.ac.uk

Other researchers

Professor Ivo Tews

Professor
Research interests
  • Natural products biosynthesis: a complex cascade of catalytic steps in vitamin B6 biosynthesis is characterised by structures or reaction intermediates in the large PLP syntase complexEdit
  • Bacterial biofilms: understanding of RedOx regulated phosphodiesterase activity in dispersal of biofilms to address chronic infections
  • Cancer immunology: together with Cancer Immunology at Southampton we use a structure based apporach in developing novel cancer therapie
Connect with Ivo

Email: Ivo.Tews@soton.ac.uk

Dr Joel Allen

Principal Research Fellow
Research interests
  • Mass spectrometry
  • Viral glycobiology
  • Immunogen design
Connect with Joel

Email: Joel.Allen@soton.ac.uk

Research outputs