Hanson RG/15/17/31749 Epigenetic Biomarkers and Determinants of Cardiovascular Risk in Children

Staff

Lead researchers

Emeritus Professor Mark Hanson

Connect with Mark

Email: M.Hanson@soton.ac.uk

Other researchers

Professor Cyrus Cooper

Prof Rheumatology Clinical Epidemiology

Research interests

Key research contributions have been:
discovery of the developmental influences which contribute to the risk of osteoporosis and hip fracture in late adulthood
demonstration that maternal vitamin D insufficiency is associated with sub-optimal bone mineral accrual in childhood

Connect with Cyrus

Email: cc@mrc.soton.ac.uk

Professor Keith Godfrey

Associate Dean Enterprise

Connect with Keith

Email: kmg@mrc.soton.ac.uk

Emeritus Professor Hazel Inskip MSc, PhD, FFPH

Connect with Hazel

Email: hmi@mrc.soton.ac.uk

Collaborating research institutes, centres and groups

Plants and Food Security

We study the response of plants to the environment at the molecular, whole plant and ecological levels. This includes interactions with nematodes, insects and microbes.

Research outputs

Adherence to Healthy Eating Index for pregnant women is associated with lower neonatal adiposity in a multi-ethnic Asian cohort

Ai-Ru Chia, Mya Thway Tint, Chad Y Han, Ling-Wei Chen, Marjorelee T. Colega, Izzuddin M. Aris, Mei Chien Chua, Kok Hian Tan, Fabian Yap, Lynette Pei-Chi Shek , Yap-Seng Chong, Keith Godfrey, Marielle V. Fortier, Yung Seng Lee & Mary Foong-Fong Chong, 2018, American Journal of Clinical Nutrition, 107(1), 71-79

DOI: 10.1093/ajcn/nqx003

Type: article

Modifiable risk factors in the first 1000 days for subsequent risk of childhood overweight in an Asian cohort

I.M. Aris, J.Y. Bernard, L.W. Chen, M.T. Tint, W.W. Pang, S.E. Soh, S.M. Saw, L.P.C. Shek, K.M. Godfrey, P.D. Gluckman, Y.S. Chong, F. Yap, M.S. Kramer & Y. S. Lee, 2018, International Journal of Obesity, 42(1), 44-51

DOI: 10.1038/ijo.2017.178

Type: article

Vitamin B₁₂ supplementation influences methylation of genes associated with Type 2 diabetes and its intermediate traits

Dilip K. Yadav, Smeeta Shrestha, Karen A. Lillycrop, Charu V. Joglekar, Hong Pan, Joanna D. Holbrook, Caroline H.D. Fall, Chittaranjan S. Yajnik & Giriraj R. Chandak, 2018, Epigenomics, 10(1), 71-90

DOI: 10.2217/epi-2017-0102

Type: article

Cord metabolic profiles in obese pregnant women

Nashita Patel, Christian Hellmuth, Olaf Uhl, Keith Godfrey, Annette Briley, Paul Welsh, Dharmintra Pauupathy, Paul T. Seed, Berthold Koletzko & Lucilla Poston, 2018, Journal of Clinical Endocrinology & Metabolism, 103(1), 346-355

DOI: 10.1210/jc.2017-00876

Type: article

Breech presentation is associated with lower bone mass and area

Alex Ireland, Sarah Crozier, Alexander E.P. Heazell, Kathryn Ward, Keith Godfrey, Hazel Inskip, Cyrus Cooper & Nicholas Harvey, 2018, Osteoporosis International, 1-7

DOI: 10.1007/s00198-018-4626-2

Type: article

DOHaD in science and society

M. Penkler, M. Hanson, R. Biesma & R. Müller, 2018, Journal of Developmental Origins of Health and Disease, 1-6

DOI: 10.1017/S2040174418000892

Type: article

DNA methylation of amino acid transporter genes in the human placenta

C. Simner, B. Novakovic, K. Lillycrop, C. Bell, N. Harvey, C. Cooper, R. Saffery, R. Lewis & J. Cleal, 2017, Placenta, 60, 64-73

DOI: 10.1016/j.placenta.2017.10.010

Type: article