Research project

J Tod MRC The role of Eps8 in regulating pancreatic cancer G1002008

Research groups:
Lead researcher:

Professor Gareth Thomas
Research funder:

Medical Research Council
Status:

Not active

Staff

Lead researcher

Professor Gareth Thomas

Professor of Experimental Pathology

Research interests

Fibroblast biology and immunology
Tumour microenvironment
Cancer Immunotherapy

Email: g.thomas@soton.ac.uk

Collaborating research institutes, centres and groups

Cancer Sciences

Our research works towards improving treatment for patients with cancer.

Research outputs

Pro-migratory and TGF-β-activating functions of αvβ6 integrin in pancreatic cancer are differentially regulated via an Eps8-dependent GTPase switch

Joanne Tod,

Christopher Hanley,

Mark R. Morgan,

Marta Rucka,

Toby Mellows,

Maria-Antoinette Lopez,

Philip Kiely,

Karwan Moutasim,

Steven, James Frampton,

Durgagauri Sabnis,

David R. Fine,

Colin Johnson,

John F. Marshall,

Giorgio Scita,

Veronika Jenei,

& Gareth Thomas

, 2017 , The Journal of Pathology , 243 (1) , 37--50

DOI: 10.1002/path.4923

Type: article

Suppression of hedgehog signalling promotes pro-tumourigenic integrin expression and function

Karwan A. Moutasim,

Toby Mellows,

Massimiliano Mellone,

Marie-Antoinette Lopez,

Joanne Tod,

Philip C. Kiely,

Karen Sapienza,

Azzura Greco,

Graham Neill,

Shelia Violette,

Paul Weinreb,

John Marshall,

Christian H. Ottensmeier,

A.E. Sayan,

V. Jenei,

& Gareth J. Thomas

, 2014 , The Journal of Pathology , 233 (2) , 196--208

DOI: 10.1002/path.4342

Type: article

Tumor-stromal interactions in pancreatic cancer

Jo Tod,

Veronika Jenei,

Gareth Thomas,

& David Fine

, 2013 , Pancreatology , 13 (1) , 1--7

DOI: 10.1016/j.pan.2012.11.311

Type: article