Research project

Phil Gale - Synthetic Anionophores with Therapeutic Potential - EP/J009687/1

Research funder:

EPSRC
Status:

Not active

Research outputs

Aromatic isophthalamides aggregate in lipid bilayers: evidence for a cooperative transport mechanism

2015, Organic & Biomolecular Chemistry

Type: article

Anion binding and transport properties of cyclic 2,6-bis(1,2,3-triazol-1-yl)pyridines

Tamara Merckx, Cally J.E. Haynes, Louise E. Karagiannidis, Harriet J. Clarke, Katie Holder, Alexandra Kelly, Graham J. Tizzard, Simon J. Coles, Peter Verwilst, Philip A. Gale & Wim Dehaen, 2015, Organic & Biomolecular Chemistry, 13(6), 1654-1661

DOI: 10.1039/c4ob02236j

Type: article

Dynamic covalent transport of amino acids across lipid bilayers

Xin Wu, Nathalie Busschaert, Neil J. Wells, Yun-Bao Jiang & Philip A. Gale, 2015, Journal of the American Chemical Society, 137(4), 1476-1484

DOI: 10.1021/ja510063n

Type: article

pH switchable anion transport by an oxothiosquaramide

2015, Chemical Communications, 51, 10107-10110

DOI: 10.1039/c5cc03625a

Type: article

Highly effective yet simple transmembrane anion transporters based upon ortho-phenylenediamine bis-ureas

Louise E. Karagiannidis, Cally J. E. Haynes, Katie J. Holder, Isabelle L. Kirby, Stephen J. Moore, Neil J. Wells & Philip A. Gale, 2014, Chemical Communications

DOI: 10.1039/c4cc05519e

Type: article

Synthetic ion transporters can induce apoptosis by facilitating chloride anion transport into cells

2014, Nature Chemistry, 6, 885-892

DOI: 10.1038/NCHEM.2021

Type: article

Synthetic transporters for sulfate: a new method for the direct detection of lipid bilayer sulfate transport

Nathalie Busschaert, Louise E. Karagiannidis, Marco Wenzel, Cally J. E. Haynes, Neil J. Wells, Philip G. Young, Damjan Makuc, Janez Plavec, Katrina A. Jolliffe & Philip A. Gale, 2014, Chemical Science, 5(3), 1118-1127

DOI: 10.1039/C3SC52006D

Type: article