Research project

Photo-Electro: Transforming Chemical Synthesis, Discovery and Manufacture

Research groups:

Organic Chemistry, Synthesis, Catalysis
Lead researcher:

Professor Richard Brown
Other researchers:

Professor David Harrowven
Research funder:

EPSRC
Status:

Not active

Staff

Lead researcher

Professor Richard Brown

Professor of Organic Chemistry

Connect with Richard

Email: r.c.brown@soton.ac.uk

Other researchers

Professor David Harrowven

Professor of Chemistry

Connect with David

Email: dch2@soton.ac.uk

Collaborating research institutes, centres and groups

Organic Chemistry, Synthesis, Catalysis

We develop environmentally sustainable approaches to chemical manufacture that minimise chemical waste, improve product velocity and reduce the need to isolate intermediates.

Research outputs

First example of organocatalysis by cathodic N-heterocyclic carbene generation and accumulation using a divided electrochemical flow cell

Daniele Rocco,

Ana Folgueiras Amador,

Richard C.D. Brown,

& Marta Feroci

, 2022 , Beilstein Journal of Organic Chemistry , 18 , 979--990

DOI: 10.3762/bjoc.18.98

Type: article

Cathodic radical cyclisation of aryl halides using a strongly-reducing catalytic mediator in flow

Ana Folgueiras Amador,

Alexander Teuten,

Mateo Salam Perez,

James Pearce,

Guy Denuault,

Derek Pletcher,

Phillip James Parsons,

David C. Harrowven,

& Richard C.D. Brown

, 2022 , Angewandte Chemie International Edition , 61 (35)

DOI: 10.1002/anie.202203694

Type: article

Self-optimization of continuous flow electrochemical synthesis using Fourier transform infrared spectroscopy and gas chromatography

Jie Ke,

Chuang Gao,

Ana A. Folgueiras-Amador,

Katherine E. Jolley,

Oscar de Frutos,

Carlos Mateos,

Juan A. Rincón,

Richard C.D. Brown,

Martyn Poliakoff,

& Michael W. George

, 2022 , Applied Spectroscopy , 76 (1) , 38--50

DOI: 10.1177/00037028211059848

Type: article

New Approaches to Ondansetron and Alosetron Inspire a Versatile, Flow Photochemical Method for Indole Synthesis

Wei Sun,

William Raimbach,

Luke D. Elliott,

Kevin I. Booker-Milburn,

& David C. Harrowven

, 2022 , ChemComm , 58 (3) , 383--386

DOI: 10.1039/D1CC05700F

Type: article

Wavelength dependent photoextrusion and tandem photoextrusion reactions of ninhydrin bis-acetals for the synthesis of 8-ring lactones, benzocyclobutenes and orthoanhydrides

David C. Harrowven,

Wei Sun,

Surajit Kayal,

William Raimbach,

Xue-Zhong Sun,

Mark Light,

Magnus W.D. Hanson-Heine,

& Michael W George

, 2021 , ChemComm

DOI: 10.1039/D1CC06800H

Type: article