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Dr Mark Andrew Burton BA (Hons), BSc (Hons), MSc, PhD

Research Fellow

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Dr Mark Burton is a postdoctoral research fellow in Epigenetics within the Faculty of Medicine at the University of Southampton.


Dr Burton completed an Undergraduate degree in Biomedical Sciences at the University of Southampton, followed by an MSc in Molecular Neurosciences at the University of Bristol. He returned to Southampton to study for his PhD investigating the effect of folic acid intake on the regulation of genes that modulate breast cancer development and how epigenetic regulation plays a role. This established an interest in the epigenetics of disease and how intervention at different periods of the life-course can modulate disease trajectories.

Dr Burton has worked on a number of research projects within the EpiGen Research Group including investigating the links between methylation adiposity and non-alcoholic fatty liver disease in adolescence, in collaboration with the University of Western Australia. He has also participated in a number of large cohort studies investigating the cellular and molecular regulation of sarcopenia, testing novel pharmacological compounds in collaboration with a UK-based artificial intelligence industry partner (BenevolentAI). Furthermore, he has worked on three pioneering projects investigating the regulation of non-coding RNA’s in serum from the Hertfordshire sarcopenia cohort, and in sperm from the PREPARE cohort, characterising for the first time the small ncRNA populations.

He recently led a project investigating the single cell transcriptomes of nuclei from cultured primary myoblasts from older people with sarcopenia. Dr Burton hopes to continue with research which will enable the discovery of biomarkers that are predictive of disease risk, to enable molecular targeting through nutritional or pharmacological intervention in order to improve health trajectories.


PhD, University of Southampton, 2017

MSc, Molecular Neuroscience, University of Bristol, 2012

BSc (Hon’s) Biomedical Sciences, University of Southampton, 2011

BA (Hon’s), Sports Studies and Psychology, University of Winchester 2003


Appointments held

Postgraduate Research Fellow in Epigenetics, University of Southampton 2017-current

Research group

Human Development and Health

Affiliate research group

Human Development and Health

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Medical Student Project Supervision

MBioSci Student Supervision

Tutorial Teaching First Year Medical Students

Dr Mark Andrew Burton
Faculty of Medicine, Room AB215, Mailpoint 801, South Academic Block, University Hospital Southampton, Tremona Road, Southampton, SO16 6YD

Room Number : SGH/IDSB03/MP887

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