Mark Andrew Burton

Publications

9 publications

Page 1 of 1

Differential DNA methylation of steatosis and non-alcoholic fatty liver disease in adolescence

Phillip E. Melton,

Mark Burton,

Karen Lillycrop,

Keith Godfrey,

Sebastian Rauschert,

D Anderson ,

Graham Burdge,

Trevor A. Mori,

L. J. Beilin,

O.T. Ayonrinde,

J.M. Craig,

J K Olynyk,

Joanna D Holbrook,

Craig E. Pennell,

Wendy H. Oddy,

E. K. Moses,

L.A. Adams,

& Rae-Chi Huang

, 2023 , Hepatology International

DOI: 10.1007/s12072-022-10469-7

Type: article

Linking nutrition to long-term health: Epigenetic mechanisms

Mark Burton,

Keith Godfrey,

& Karen Lillycrop

, 2022

DOI: 10.1016/b978-0-12-824389-3.00017-9

Type: bookChapter

Short-term diet intervention alters the small non-coding RNA (sncRNA) landscape of human sperm

C Vaz,

AJ Kermack,

M Burton,

PF Tan,

J Huan,

TPX Yoo,

Kerry Donnelly,

SJ Wellstead,

HL Fisk,

FD Houghton,

S Lewis,

YS Chong,

PD Gluckman,

Y Cheong,

& N Karnani

, 2021

DOI: 10.1101/2021.07.08.451257

Type: other

Adiposity associated DNA methylation signatures in adolescents are related to leptin and perinatal factors

R.C. Huang,

P.E. Melton,

M.A. Burton,

L.J. Beilin,

R. Clarke-Harris,

E. Cook,

K.M. Godfrey,

G.C. Burdge,

T.A. Mori,

D Anderson ,

S. Rauschert,

J.M. Craig,

M.S. Kobor,

J.L. MacIsaac,

A.M. Morin,

W.H. Oddy,

C.E. Pennell,

J.D. Holbrook,

& K.A. Lillycrop

, 2021 , Epigenetics

DOI: 10.1080/15592294.2021.1876297

Type: article

Epigenome-wide association study of sarcopenia

Elie Antoun,

Emma Garratt,

Andrea Taddei,

Mark Burton,

Sheila Barton,

Philip Titcombe,

Leo Westbury,

Alicia Baczynska,

Eugenia Migliavacca,

Jerome N. Feige,

Holly Emma Syddall,

Elaine Dennison,

Richard Dodds,

Helen Roberts,

Peter Richardson,

Avan A. Sayer,

Sarah Shaw,

Cyrus Cooper,

Joanna D. Holbrook,

Harnish Patel,

Keith Godfrey,

& Karen Lillycrop

, 2021 , Journal of Cachexia, Sarcopenia and Muscle

DOI: 10.1002/jcsm.12876

Type: article

High maternal folic acid intake around conception alters mouse blastocyst lineage allocation and expression of key developmental regulatory genes

R. S. Penailillo,

M. A. Burton,

G. C. Burdge,

T. P. Fleming,

& K. A. Lillycrop

, 2021 , Molecular Reproduction and Development , 88 (4) , 261--273

DOI: 10.1002/mrd.23462

Type: article

Folic acid induces intake-related changes in the mammary tissue transcriptome of C57BL/6 mice

Mark A Burton,

Elie Antoun,

Reyna S Penailillo,

Graham C Burdge,

& Karen A Lillycrop

, 2020 , Nutrients , 12 (9) , 1--13

DOI: 10.3390/nu12092821

Type: article

Nutritional modulation of the epigenome and its implication for future health

Mark A. Burton,

& Karen A. Lillycrop

, 2019 , Proceedings of the Nutrition Society , 1--8

DOI: 10.1017/S0029665119000016

Type: article

The effect of the level and timing of folic acid supplementation during the life course on the regulation of breast cancer determining genes, mammary morphology and implications for genome stability and tissue differentiation

Mark Andrew Burton

, 2016

Type: thesis

Biography

Dr Burton completed an Undergraduate degree in Biomedical Sciences at the University of Southampton, followed by an MSc in Molecular Neurosciences at the University of Bristol. He returned to Southampton to study for his PhD investigating the effect of folic acid intake on the regulation of genes that modulate breast cancer development and how epigenetic regulation plays a role. This established an interest in the epigenetics of disease and how intervention at different periods of the life-course can modulate disease trajectories. Dr Burton has worked on a number of research projects within the EpiGen Research Group including investigating the links between methylation adiposity and non-alcoholic fatty liver disease in adolescence, in collaboration with the University of Western Australia. He has also participated in a number of large cohort studies investigating the cellular and molecular regulation of sarcopenia, testing novel pharmacological compounds in collaboration with a UK-based artificial intelligence industry partner (BenevolentAI). Furthermore, he has worked on three pioneering projects investigating the regulation of non-coding RNA’s in serum from the Hertfordshire sarcopenia cohort, and in sperm from the PREPARE cohort, characterising for the first time the small ncRNA populations. He recently ran a project investigating the single cell transcriptomes of nuclei from cultured primary myoblasts from older people with sarcopenia. Dr Burton hopes to continue with research which will enable the discovery of biomarkers that are predictive of disease risk, to enable molecular targeting through nutritional or pharmacological intervention in order to improve health trajectories.

Dr Mark Burton

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Publications

Biography