Irene Mary Stratton

Research

Research interests

Diabetic Retinopathy
Clinical Trials
Ophthalmology
Prediction modelling
Screening

Current research

Diabetes

Diabetic retinopathy

Prediction modelling

Publications

50 publications

Page 1 of 5

A foundation model for generalizable disease detection from retinal images

Yukun Zhou,

Mark A. Chia,

Siegfried K. Wagner,

Murat S. Ayhan,

Dominic J. Williamson,

Robbert R. Struyven,

Timing Liu,

Moucheng Xu,

Mateo G. Lozano,

Peter Woodward-Court,

Yuka Kihara,

Naomi Allen,

John E.J. Gallacher,

Thomas Littlejohns,

Tariq Aslam,

Paul Bishop,

Graeme Black,

Panagiotis Sergouniotis,

Denize Atan,

Andrew D. Dick,

Cathy Williams,

Sarah Barman,

Jenny H. Barrett,

Sarah Mackie,

Tasanee Braithwaite,

Roxana O. Carare,

Sarah Ennis,

Jane Gibson,

Andrew J. Lotery,

Jay Self,

Usha Chakravarthy,

Ruth E. Hogg,

Euan Paterson,

Jayne Woodside,

Tunde Peto,

Gareth Mckay,

Bernadette Mcguinness,

Paul J. Foster,

Konstantinos Balaskas,

Anthony P. Khawaja,

Nikolas Pontikos,

Jugnoo S. Rahi,

Gerassimos Lascaratos,

Praveen J. Patel,

Michelle Chan,

Sharon Y.L. Chua,

Alexander Day,

Parul Desai,

James E. Morgan,

& Irene Stratton

, 2023 , Nature , 622 (7981) , 156--163

DOI: 10.1038/s41586-023-06555-x

Type: article

A new polygenic score for refractive error improves detection of children at risk of high myopia but not the prediction of those at risk of myopic macular degeneration

Rosie Clark,

Samantha Sze Yee Lee,

Ran Du,

Yining Wang,

Sander C.M. Kneepkens,

Jason Charng,

Yu Huang,

Michael L. Hunter,

Chen Jiang,

J. Willem L. Tideman,

Ronald B. Melles,

Caroline C.W. Klaver,

David A. Mackey,

Cathy Williams,

Hélène Choquet,

Kyoko Ohno-Matsui,

Jeremy A. Guggenheim,

Joan E. Bailey-Wilson,

Paul N. Baird,

Veluchamy A. Barathi,

Ginevra Biino,

Kathryn P. Burdon,

Harry Campbell,

Li Jia Chen,

Ching Yu Cheng,

Emily Y. Chew,

Jamie E. Craig,

Margaret M. Deangelis,

Cécile Delcourt,

Xiaohu Ding,

Qiao Fan,

Maurizio Fossarello,

Paul J. Foster,

Puya Gharahkhani,

Xiaobo Guo,

Annechien E.G. Haarman,

Toomas Haller,

Christopher J. Hammond,

Xikun Han,

Caroline Hayward,

Qing Li,

Nicholas G. Martin,

James F. Wilson,

Roxana Carare,

Sarah Ennis,

Jane Gibson,

Andrew Lotery,

James Morgan,

Jay Self,

& Irene Stratton

, 2023 , EBioMedicine , 91

DOI: 10.1016/j.ebiom.2023.104551

Type: article

UK Biobank retinal imaging grading: methodology, baseline characteristics and findings for common ocular diseases

Alasdair N. Warwick,

Katie Curran,

Barbra Hamill,

Kelsey Stuart,

Anthony P. Khawaja,

Paul J. Foster,

Andrew J. Lotery,

Michael Quinn,

Savita Madhusudhan,

Konstantinos Balaskas,

Tunde Peto,

N. Allen,

T. Aslam,

D. Atan,

S. Barman,

J. Barrett,

P. Bishop,

G. Black,

T. Braithwaite,

R. Carare,

U. Chakravarthy,

M. Chan,

S. Chua,

A. Day,

P. Desai,

B. Dhillon,

A. Dick,

A. Doney,

C. Egan,

S. Ennis,

P. Foster,

M. Fruttiger,

J. Gallacher,

D. Garway-Heath,

J. Gibson,

C. Hammond,

A. Hardcastle,

S. Harding,

Andrew J. Lotery,

T. Moore,

J. Morgan,

C. Owen,

P. Patel,

J. Self,

I. Stratton,

Z. Sun,

D. Thomas,

K. Williams,

C. Williams,

& Y. Zheng

, 2023 , Eye , 37 (10) , 2109--2116

DOI: 10.1038/s41433-022-02298-7

Type: article

Correction

Alasdair N. Warwick,

Katie Curran,

Barbra Hamill,

Kelsey Stuart,

Anthony P. Khawaja,

Paul J. Foster,

A. Lotery,

Michael Quinn,

Savita Madhusudhan,

Konstantinos Balaskas,

Tunde Peto,

N. Allen,

T. Aslam,

D. Atan,

S. Barman,

J. Barrett,

P. Bishop,

G. Black,

T. Braithwaite,

R. Carare,

U. Chakravarthy,

M. Chan,

S. Chua,

A. Day,

P. Desai,

B. Dhillon,

A. Dick,

A. Doney,

C. Egan,

S. Ennis,

P. Foster,

M. Fruttiger,

J. Gallacher,

D. Garway-Heath,

J. Gibson,

C. Hammond,

A. Hardcastle,

S. Harding,

A. Lotery,

T. Moore,

J. Morgan,

C. Owen,

P. Patel,

J. Self,

I. Stratton,

Z. Sun,

D. Thomas,

K. Williams,

C. Williams,

& Ying Zheng

, 2023

DOI: 10.1038/s41433-022-02377-9

Type: letterEditorial

The association between serum lipids and intraocular pressure in 2 large United Kingdom cohorts

Kian M. Madjedi,

Kelsey V. Stuart,

Sharon Y.L. Chua,

Robert N. Luben,

Alasdair Warwick,

Louis R. Pasquale,

Jae H. Kang,

Janey L. Wiggs,

Marleen A.H. Lentjes,

Hugues Aschard,

Naveed Sattar,

Paul J. Foster,

Anthony P. Khawaja,

Mark Chia,

Ron Do,

Alan Kastner,

Jihye Kim,

Giovanni Montesano,

Denize Atan,

Tariq Aslam,

Sarah A. Barman,

Jenny H. Barrett,

Paul Bishop,

Peter Blows,

Catey Bunce,

Roxana O. Carare,

Usha Chakravarthy,

Michelle Chan,

David P. Crabb,

Philippa M. Cumberland,

Alexander Day,

Parul Desai,

Bal Dhillon,

Andrew D. Dick,

Cathy Egan,

Sarah Ennis,

Paul Foster,

Marcus Fruttiger,

John E.J. Gallacher,

David F. Garway-Heath,

Jane Gibson,

Dan Gore,

Jeremy A. Guggenheim,

Chris J. Hammond,

Alison Hardcastle,

Simon P. Harding,

Andrew J. Lotery,

James E. Morgan,

Jay Self,

& Irene Stratton

, 2022 , Ophthalmology , 129 (9) , 986--996

DOI: 10.1016/j.ophtha.2022.04.023

Type: article

The association of alcohol consumption with glaucoma and related traits

Kelsey Stuart,

Robert N. Luben,

Alasdair N. Warwick,

Kian Madjedi,

Praveen J. Patel,

Mahantesh I. Biradar,

Zihan Sun,

Mark Chia,

Louis Pasquale,

Janey Wiggs,

Jae H. Kang,

Jihye Kim,

Hugues Aschard,

Jessica H. Tran,

Marleen Lentjes,

Paul J. Foster,

Anthony Khawaja,

Mark Chia,

Sharon Chua,

Ron Do,

Paul Foster,

Jae Kang,

Alan Kastner,

Anthony Khawaja,

Marleen Lentjes,

Robert Luben,

Kian Madjedi,

Giovanni Montesano,

Louis Pasquale,

Kelsey Stuart,

Alasdair Warwick,

Janey Wiggs,

Naomi Allen,

Tariq Aslam,

Denize Atan,

Sarah Barman,

Jenny Barrett,

Paul Bishop,

Graeme Black,

Roxana Carare,

Sarah Ennis,

Jane Gibson,

Andrew Lotery,

James Morgan,

Jay Self,

Irene Stratton,

Li Chen,

Ching Yu Cheng,

Angela Cree,

& James Wilson

, 2022 , Ophthalmology Glaucoma

DOI: 10.1016/j.ogla.2022.11.008

Type: article

Retinal asymmetry in multiple sclerosis

Axel Petzold,

Sharon Y.L. Chua,

Anthony P. Khawaja,

Pearse A. Keane,

Peng T. Khaw,

Charles Reisman,

Baljean Dhillon,

Nicholas G. Strouthidis,

Paul J. Foster,

Praveen Patel,

Denize Atan,

Tariq Aslam,

Sarah A. Barman,

Jenny H. Barrett,

Paul Bishop,

Catey Bunce,

Roxana O. Carare,

Usha Chakravarthy,

Michelle Chan,

Sharon Y.L. Chua,

David P. Crabb,

Alexander Day,

Parul Desai,

Bal Dhillon,

Andrew D. Dick,

Cathy Egan,

Sarah Ennis,

Paul J. Foster,

Marcus Fruttiger,

John E.J. Gallacher,

David F. Garway-Heath,

Jane Gibson,

Dan Gore,

Jeremy A. Guggenheim,

Chris J. Hammond,

Alison Hardcastle,

Simon P. Harding,

Ruth E. Hogg,

Pirro Hysi,

Pearse A. Keane,

Sir Peng T. Khaw,

Anthony P. Khawaja,

Gerassimos Lascaratos,

Andrew J. Lotery,

Tom MacGillivray,

Sarah MacKie,

Michelle McGaughey,

James E. Morgan,

Jay Self,

& Irene Stratton

, 2021 , Brain , 144 (1) , 224--235

DOI: 10.1093/brain/awaa361

Type: article

Investigation of associations between retinal microvascular parameters and albuminuria in UK Biobank

Euan N. Paterson,

Chris Cardwell,

Thomas J. MacGillivray,

Emanuele Trucco,

Alexander S. Doney,

Paul Foster,

Alexander P. Maxwell,

Gareth McKay,

Tariq Aslam,

Sarah Barman,

Jenny Barrett,

Paul Bishop,

Peter Blows,

Catey Bunce,

Roxana Carare,

Usha Chakravarthy,

Michelle Chan,

Antonietta Chianca,

Valentina Cipriani,

David Crabb,

Philippa Cumberland,

Alexander Day,

Parul Desai,

Bal Dhillon,

Andrew Dick,

Cathy Egan,

Sarah Ennis,

Marcus Fruttiger,

John Gallacher,

David (Ted) Garway-Heath,

Jane Gibson,

Dan Gore,

Jeremy Guggenheim,

Chris Hammond,

Alison Hardcastle,

Simon Harding,

Ruth Hogg,

Pirro Hysi,

Pearse A. Keane,

Sir Peng Tee Khaw,

Anthony Khawaja,

Gerassimos Lascaratos,

Andrew Lotery,

Phil Luthert,

Tom MacGillivray,

Sarah Mackie,

Keith Martin,

James Morgan,

Jay Self,

& Irene Stratton

, 2021 , BMC Nephrology , 22 (1) , 72

DOI: 10.1186/s12882-021-02273-6

Type: article

Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries

Puya Gharahkhani,

Eric Jorgenson,

Pirro Hysi,

Anthony P. Khawaja,

Sarah Pendergrass,

Xikun Han,

Jue Sheng Ong,

Alex W. Hewitt,

Ayellet V. Segrè,

John M. Rouhana,

Andrew R. Hamel,

Robert P. Igo,

Helene Choquet,

Ayub Qassim,

Navya S. Josyula,

Jessica N. Cooke Bailey,

Pieter W.M. Bonnemaijer,

Adriana Iglesias,

Owen M. Siggs,

Terri L. Young,

Veronique Vitart,

Alberta A.H.J. Thiadens,

Juha Karjalainen,

Steffen Uebe,

Ronald B. Melles,

K. Saidas Nair,

Robert Luben,

Mark Simcoe,

Nishani Amersinghe,

Angela J. Cree,

Rene Hohn,

Alicia Poplawski,

Li Jia Chen,

Shi Song Rong,

Tin Aung,

Sarah Martin,

Andrew J. White,

Roxana Carare,

Sarah Ennis,

Paul Foster,

Jane Gibson,

Andrew J. Lotery,

James E. Morgan,

Jay Self,

Irene Stratton,

Xin Wang,

Nicholas G. Martin,

James E. Morgan,

Andrew J. Lotery,

& Ching Yu Cheng

, 2021 , Nature Communications , 12 (1)

DOI: 10.1038/s41467-020-20851-4

Type: article

Glycaemic control and familial factors determine hyperlipidaemia in early childhood diabetes

A. Abraha,

C. Schultz,

T. Konopelska-Bahut,

T. James,

A. Watts,

I. M. Stratton,

D. R. Matthews,

& David B. Dunger

, 1999 , Diabetic Medicine , 16 (7) , 598--604

DOI: 10.1046/j.1464-5491.1999.00109.x

Type: article

Mrs Irene Stratton

Research interests

Research

Research interests

Current research

Publications

Biography

Prizes