Much of cochlear physiology and pathophysiology remains poorly understood. For example, how do the 3000 rows of active outer hair cells interact with each other and with other cochlear structures to amplify the waves in the cochlea that allow us to hear? How are the motions of these cochlear structures related to the otoacoustic emissions that we can measure in the ear canal? What role do the efferent nerves play? What are the changes brought about by pathology? The long term research goal is to understand human cochlear physiology in both normal and pathological conditions with a view to aiding the development of improved clinical diagnostic techniques and treatments. One approach to improving our understanding of the electro-mechanical aspect of physiology is to develop realistic models of the cochlea. These should capture the essential hydrodynamics, structural dynamics, and electrical processes involved in cochlear physiology. The non-linear mechano-electrical and electro-mechanical transduction processes are key aspects of the physiology where our understanding remains at a basic level. The ways in which these models may be useful clinically are: to aid the development of treatments, or prostheses for hearing impairment, to improve our ability to interpret clinical results (such as measurements of otoacoustic emissions or electrophysiology), to aid the development of new clinical tests of cochlear function.
Autonomous robotic platforms allow detailed observations to be made over large areas in the ocean. For these systems to be useful, it is necessary to develop advanced sensing capabilities and methods to allow the robots to safely navigate and accurately localize themselves in complex, GPS denied environments. Once observations have been made, it’s necessary to interpret the large volumes of data that are gathered in an efficient and scalable way. For more information on research activities, please visit the Ocean Perception research website.
Seafloor 3D visual reconstruction: Development of deep-sea imaging hardware and processing pipelines for calibration, localisation and 3D mapping of the seafloor with full-field uncertainty characterisation.
BioCam (NERC NE/P020887/1): Development of a deep-sea, high-altitude seafloor imaging system for monitoring seafloor ecological variables as part of the Oceanids Marine Sensor Capital program. This project is a collaboration with Sonardyne International Ltd, the National Oceanography Centre and the ACFR University of SydneyAT-SEA (NERC NE/T010592/1): 3D visual survey of decommissioned seafloor infrastructure using a shore launched Autonomous Underwater Vehicle (Boaty McBoaface) as part of the INSITE program. This project is a collaboration with the National Oceanography Centre.
Automated interpretation of data: Development of AI methods for rapid scalable interpretation of seafloor imagery.
Creep, fatigue as well as oxidationResidual stresses at different length-scalesHigh-temperature structural integrity assessmentElectron beam melting and other powder-bed-fusion additive manufacturing processes (experiment and process model)Physical metallurgy of high-temperature structural materialsTitanium alloys and gamma-TiAl alloysNickel base superalloysAustenitic stainless steelsLarge scale experimental facilities (neutron and synchrotron X-ray based)Advanced electron microscopy
