Biomedical digital and virtual microscopy facility

About the Biomedical digital and virtual microscopy facility

Think Google Earth for microscope slides!

Virtual microscopy systems allow you to scan an entire slide or selected regions of a slide at a chosen magnification and then zoom in and out and navigate around the scanned slide.

Scans are stored as individual image tiles which are assembled/montaged on the fly for low band width, high-resolution viewing. Our systems are equipped with adjustable sensitivity tissue content recognition and manual override. Our high throughput system can combine 4 channel fluorescent imaging with brightfield or phase contrast imaging (selected magnifications only for phase contrast).

Technical specification

Olympus dotSlide virtual microscopy system (x2)

  • Olympus BX51 microscope frame with 4 place slide holder
  • automated slide scanning/virtual microscopy system with ultra-high quality, colour Olympus CC12 microscope camera
  • brightfield imaging
  • objective range x4 to x60
  • slide holder for single 3x2 inch slides
  • tissue microarray module for assembly of tiles from single cores of TMAs into single images
     

Olympus VS110 high throughput virtual microscopy system

  • Olympus BX51 microscope frame with 100 place robotic slide loader (3x1 inch slides only)
  • Olympus VS software control
  • automated slide scanning/virtual microscopy system with bright field, phase contrast and fluorescence imaging and scanning
  • high quality, Allied Vision Technology colour, microscope camera for brightfield and high quality Olympus XM10 monochrome camera for fluorescence
  • brightfield imaging, phase contrast (x10 only) and fluorescence imaging
  • objective range x2 to x40
  • DAPI/FITC/Cy3/Cy5 filter sets (with quad band dichroic and fast excitation filter wheel)
  • Olympus VS desktop software (10 user network licence) for remote analysis of scanned slides
  • Z series, extended focus imaging and fluorescence maximum projection options
  • scan to database option

Contact us

Contact us

We are based in the Laboratory and Pathology block at Southampton General Hospital.
We’re open Monday to Friday 09:00 to 17:00 UK time.