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Biomedical spatial biology facility

Patricia Goggin uses a high tech imaging device.

About the Biomedical spatial biology facility

Nature Methods chose spatially resolved transcriptomics as the method of the year in 2020.

We have built a spatial biology platform, where we aim to host a suite of equipment and corresponding expertise to enable our researchers to carry out cutting edge work on medically relevant challenges.

We provide advice on and support experimental design, sample preparation and data analysis.

Technical specification

Nanostring CosMx

  • Spatial molecular imaging
  • High plex in-situ analysis
  • RNA and protein analysis
  • Formalin-fixed paraffin-embedded (FFPE) and fresh frozen (FF) tissue samples
     

Nanostring GeoMx

  • Digital spatial profiling
  • Non-destructive profiling of RNA and protein expression from distinct tissue compartments and cell populations
  • Spatially profile the whole transcriptome and 570+ protein targets
  • Formalin-fixed paraffin-embedded (FFPE) and fresh frozen (FF) tissue samples
  • Integrates with standard histology staining
     

AtomX

  • Spatial informatics platform
  • Cloud-based, fully-integrated informatics platform
  • Analysis and visualisation of spatial multiomics data using NanoString-configured analysis modules and pipelines
  • Custom analysis modules and pipelines can be created and executed

Contact us

Contact us

023 8120 4815/UHS x4815
spatial@soton.ac.uk
BIU@soton.ac.uk
We are based in the Laboratory and Pathology block at Southampton General Hospital.
(Open in Google maps)
We’re open Monday to Friday 09:00 to 17:00 UK time.

Related research areas

Biological sciences

From global warming to life-threatening infections, we're working with industry and academic partners to tackle society's biggest challenges.

Engineering

From sustainable energy to resilient infrastructure, we're addressing some of the biggest challenges facing modern society.

Medicine

We have an international reputation for making important scientific discoveries in the lab and translating them into successful clinical treatments.

Ocean and earth science

We’re a major European centre for oceanography and marine geoscience. In the 2021 Research Excellence Framework 98% of our overall research was rated world leading or internationally excellent.

Chemistry and chemical engineering

We deliver research with real impact, from helping clinicians prescribe the most effective cancer treatments to accelerating improvements in solar power.

Physics and astronomy

Our work is centred around astronomy, quantum light and matter, and theoretical particle physics.

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3D X-ray imaging facility

We carry out advanced three-dimensional imaging and computed tomography.
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Imaging and microscopy centre

The Imaging and Microscopy Centre is a core facility for advanced life sciences imaging at Southampton University.
Person in lab coat using light microscope with digital camera attachment

Histochemistry research facility

We process cells and tissue samples into a range of mediums including frozen, paraffin, and resin.