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Research project

A Lotery MRC Self

Staff

Lead researcher

Professor Andrew Lotery

Professor of Ophthalmology

Research interests

  • Ocular clinical trials
  • Age related macular degeneration
  • Central serous chorioretinopathy

Collaborating research institutes, centres and groups

Clinical Neurosciences

Examining how clinical and environmental factors can affect brain development.

Research outputs

Evidence that the Ser192Tyr/Arg402Gln in cis Tyrosinase gene haplotype is a disease-causing allele in oculocutaneous albinism type 1B (OCA1B)
Siying Lin,
Aida Sanchez-Bretano,
Joseph S Leslie,
Katie B Williams,
Helena Lee,
Nicholas Thomas,
Jonathan L Callaway,
James Deline,
J. Arjuna Ratnayaka,
Diana Baralle,
Melanie A Schmitt,
Chelsea S Norman,
Sheri Hammond,
V. Gaurav Harlalka,
Sarah Ennis,
Harold E. Cross,
Olivia Wenger,
Andrew H. Crosby,
Emma L. Baple,
& James Self
, 2022 , npj Genomic Medicine , 7 (1) , 2
DOI: 10.1038/s41525-021-00275-9
Type: article
Novel therapeutics in nystagmus- what has the genetics taught us so far?
James Self,
& Helena Lee
, 2021 , Therapeutic Advances in Rare Disease (TAIRD)
DOI: 10.1177/2633004021998714
Type: article
Supranuclear eye movements and nystagmus in children
D. Osborne,
M. Theodorou,
H. Lee,
M. Ranger,
M. Hedley-Lewis,
F. Shawkat,
C.M. Harris,
& J.E. Self
, 2019 , Eye , 33 (2) , 261--273
DOI: 10.1038/s41433-018-0216-y
Type: article
Mutations in TYR and OCA2 associated with oculocutaneous albinism in Pakistani families
Muhammad Waqar Arshad,
Gaurav V. Harlalka,
Siying Lin,
Ilaria D'Atri,
Sarmad Mehmood,
Muhammad Shakil,
Muhammad Jawad Hassan,
Barry A. Chioza,
Jay E. Self,
Sarah Ennis,
Luke O'Gorman,
Chelsea Norman,
Tahir Aman,
Shaheer Sabz Ali,
Haiba Kaul,
Emma L. Baple,
Andrew H. Crosby,
Muhammad Ikram Ullah,
& Muhammad Imran Shabbir
, 2018 , Meta Gene , 17 , 48--55
DOI: 10.1016/j.mgene.2018.03.007
Type: article
Identification of a functionally significant tri-allelic genotype in the Tyrosinase gene (TYR) causing hypomorphic oculocutaneous albinism (OCA1B)
Chelsea S. Norman,
Luke O'Gorman,
Jane Gibson,
Reuben J. Pengelly,
Diana Baralle,
J. Arjuna Ratnayaka,
Helen Griffiths,
Matthew Rose-Zerilli,
Megan Ranger,
David Bunyan,
Helena Lee,
Rhiannon Page,
Tutte Newall,
Fatima Shawkat,
Christopher Mattocks,
Daniel Ward,
Sarah Ennis,
& Jay E. Self
, 2017 , Scientific Reports , 7 , 1--9
DOI: 10.1038/s41598-017-04401-5
Type: article
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