Research project

Investigating lipophilicity and hydrogen bonding properties of functionalised aliphatic compounds

Research groups:

Cell and Developmental Biology

Organic Chemistry, Synthesis, Catalysis
Other researchers:

Professor Phil Williamson
Research funder:

EPSRC
Status:

Not active

Staff

Other researchers

Professor Phil Williamson

Head of School

Research interests

Molecular processes underpinning neurodegenerative disease
Structure and function of cell membranes
Development and application of solid-state NMR and other biophysical techniques for the analysis of biological systems

Connect with Phil

Email: p.t.williamson@soton.ac.uk

Collaborating research institutes, centres and groups

Organic Chemistry, Synthesis, Catalysis

We develop environmentally sustainable approaches to chemical manufacture that minimise chemical waste, improve product velocity and reduce the need to isolate intermediates.

Research outputs

Reducing the lipophilicity of perfluoroalkyl groups by CF2–F/CF2-Me or CF3/CH3 exchange’

Benjamin Jeffries,

Zhong Wang,

Jérôme Graton,

Simon Holland,

Thomasin Brind,

Ryan D.R. Greenwood,

Jean-Yves Le Questel,

James S. Scott,

Elisabetta Chiarparin,

& Bruno Linclau

, 2018 , Journal of Medicinal Chemistry , 61 (23) , 10602--10618

DOI: 10.1021/acs.jmedchem.8b01222

Type: article