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Research project

Investigating the role of PIP4K2B, nuclear phosphoinositides and TAF3 in transcription and genome organisation during myogenic differentiation

  • Lead researcher:
    Professor Nullin Divecha
  • Research funder:
    Biotechnology & Biological Sciences Research Council
  • Status:
    Not active

Staff

Lead researcher

Professor Nullin Divecha

Professor of Cellular Signalling

Research outputs

Exploring the controversial role of PI3K signalling in CD4+ regulatory T (T-Reg) cells
Alessandro Poli,
Roberta Fiume,
Sara Mongiorgi,
Antonio Zaurito,
Bhavwanti Sheth,
Magdalena Castellano Vidalle,
Shidqiyyah Abdul Hamid,
Scottt. Kimber,
Francesca Campagnoli,
Stefano Ratti,
Isabella Rusciano,
Irene Faenza,
Lucia Manzoli,
& Nullin Divecha
, 2020 , Advances in Biological Regulation , 76 , 100722
DOI: 10.1016/j.jbior.2020.100722
Type: article
Nuclear phosphoinositides
R. Fiume,
I. Faenza,
B. Sheth,
A. Poli,
M. C. Vidalle,
C. Mazzetti,
S. H. Abdul,
F. Campagnoli,
M. Fabbrini,
S. T. Kimber,
G. A. Mariani,
J. Xian,
M. V. Marvi,
S. Mongiorgi,
Z. Shah,
& N. Divecha
, 2019 , International Journal of Molecular Sciences , 20 (12)
DOI: 10.3390/ijms20122991
Type: review
Phosphatidylinositol 5 phosphate (Pi5p)
Alessandro Poli,
Antonio Enrico Zaurito,
Shidqiyyah Abdul-Hamid,
Roberta Fiume,
Irene Faenza,
& Nullin Divecha
, 2019 , International Journal of Molecular Sciences , 20 (9)
DOI: 10.3390/ijms20092080
Type: review
Proteomic analysis of azacitidine-induced degradation profiles identifies multiple chromatin and epigenetic regulators including Uhrf1 and Dnmt1 as sensitive to azacitidine
Emily H. Bowler,
Joseph Bell,
Nullin Divecha,
Paul Skipp,
& Rob M. Ewing
, 2019 , Journal of Proteome Research , 18 (3) , 1032--1042
DOI: 10.1021/acs.jproteome.8b00745
Type: article
Deep proteomic analysis of Dnmt1 mutant/hypomorphic colorectal cancer cells reveals dysregulation of epithelial-mesenchymal transition and subcellular re-localization of Beta-Catenin
Emily H. Bowler,
Alex Smith-Vidal,
Alex Lester,
Joseph Bell,
Zhenghe Wang,
Christopher Bell,
Yihua Wang,
Nullin Divecha,
Paul Skipp,
& Rob M. Ewing
, 2019 , Epigenetics , 15 (1-2) , 107--121
DOI: 10.1080/15592294.2019.1656154
Type: article