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Research project

Microfluidic Platelet Profiling: Linking Platelet Reactivity With Molecular Signatures For Thrombosis Risk Prediction

Lead researcher:

Dr Jonathan West
Other researchers:

Dr Nicola Englyst,

Dr Jane Gibson,

Professor Diana Baralle
Research funder:

British Heart Foundation
Status:

Active

Staff

Lead researcher

Doctor Jonathan West

Dr Jonathan West

Associate Professor

Research interests

Platelet Diversity The lab has a keen interest in understanding the nature and consequences of platelet functional diversity. Using a droplet microfluidics strategy we can measure intrinsic platelet behaviour. Broad-continuum sensitivity was identified, with hypersensitive platelets able to drive heterotypic system polarisation. Current research aims at characterising platelet dynamics and transcriptome remodelling in response to stimulation to pin-point sub-populations governing thrombosis.

Connect with Jonathan

Email: j.j.west@soton.ac.uk

Other researchers

Doctor Nicola Englyst

Dr Nicola Englyst

Principal Teaching Fellow

Research interests

Educational projects
Patient-centred language in social media
Lab based research (collaborative) on platelets and microvesicles

Connect with Nicola

Email: n.a.englyst@soton.ac.uk

Doctor Jane Gibson

Dr Jane Gibson

Lecturer in Cancer B'infmtics & Genomics

Connect with Jane

Email: j.gibson@soton.ac.uk

Professor Diana Baralle

Professor Diana Baralle B.Sc., M.B.B.S, M.D, FRCP

Associate Dean Research

Research interests

RNA
Splicing
Genomics

Connect with Diana

Email: d.baralle@soton.ac.uk

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