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Research project

Modulating GABAergic Signalling to Augment the Immunotherapy of Solid Tumours

Staff

Lead researcher

Doctor Yury Bogdanov

Lecturer in Transgenic Technologies

Research interests

  • Tumour microenvironment
  • Neurotransmitters in Cancer

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Other researchers

Professor Mark Cragg

Professor in Experimental Cancer Biology

Research interests

  • Antibody biology
  • Antibody engineering

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Professor Stephen Beers

Professor of Immunology & Immunotherapy

Research interests

  • Edit
  • Antibody Effector Functions Monoclonal antibodies (mAb) have become established in the treatment of a variety of malignancies - transforming patient outcomes. Despite this undoubted impact, responses remain variable and their mechanisms of action and of tumour resistance are controversial. Our research is focussed on understanding these complex processes using a variety of complementary models and systems to better inform antibody selection, design and clinical application.

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Collaborating research institutes, centres and groups

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