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Research project

NIHR Southampton Biomedical Research Centre 2017-2022

Staff

Lead researcher

Professor Robert Read

Chair of Infectious Diseases

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Other researchers

Professor Chris Byrne

Professor of Endocrinol & Met

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Professor Cyrus Cooper

Prof Rheumatology Clinical Epidemiology

Research interests

  • Key research contributions have been:
  • discovery of the developmental influences which contribute to the risk of osteoporosis and hip fracture in late adulthood

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Professor Graham Roberts

Prof in Paed. Allergy & Resp. Medicine

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Professor Philip Calder

Head of School

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Professor Ratko Djukanovic

Professor of Medicine

Research interests

  • Professor Djukanovic has a lifelong interest in asthma, especially its severe forms. where his focus is on: 1) underlying pathobiological mechanisms of asthma, 2) stratification of asthma into clinical phenotypes and mechanism-based endotypes, 3) unmet needs of severe asthma management. He also has an interest in the mechanisms and treatments of severe viral infections of the lung.
  • Underlying mechanisms of asthma: Professor Djukanovic has conducted pioneer studies into the pathology of asthma, applying research bronchoscopy  (with endobronchial biopsy and bronchoalveolar lavage) and sputum induction. He led the initial task forces which defined the use of these two techniques, thereby paving the way for standardised research approches that enabled in-depth descriptions of the roles of various inflammatory cells and their mediators. He developed an explant model, consisting of bronchial biopsies placed into tissue culture, that could be stimulated ex vivo with relevant triggers, applying as needed, novel agents not yet approved for in vivo use in humans volunteers. 

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Professor Keith Godfrey

Associate Dean Enterprise

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Professor Hasan Arshad

Prof in Allergy & Clinical Immunology

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Professor Saul Faust MBBS, FRCPCH, PhD, FHEA, OBE

Professor Paediatric Immunology & Infect

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Doctor Stephen Wootton PhD FAfN OBE

Associate Professor

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Research outputs

Doxycycline for the prevention of progression of COVID-19 to severe disease requiring intensive care unit (ICU) admission: A randomized, controlled, open-label, parallel group trial (DOXPREVENT.ICU)
Raja Dhar,
John Kirkpatrick,
Laura Gilbert,
Arjun Khanna,
Mahavir Madhavdas Modi,
Rakesh K Chawla,
Sonia Dalal,
Venkata Nagarjuna Maturu,
Marcel Stern,
Oliver T Keppler,
Ratko Djukanovic,
& Stephan D Gadola
, 2023 , PLoS ONE , 18 (1) , e0280745
DOI: 10.1371/journal.pone.0280745
Type: article
Association of plasma kynurenine pathway metabolite concentrations with metabolic health risk in pre-pubertal Asian children
Karen Mei Ling Tan,
Mya Thway Tint,
Narasimhan Kothandaraman,
Fabian Yap,
Keith Godfrey,
Yung Seng Lee,
Kok Hian Tan,
Peter D. Gluckman,
Yap Seng Chong,
Mary F.F. Chong,
Johan G. Eriksson,
& David Cameron-Smith
, 2022 , International Journal of Obesity , 46 (6) , 1128--1137
DOI: 10.1038/s41366-022-01085-4
Type: article
"It is really just brilliant to get credits for something that is so important to you!" Skills for Life: University students' perceptions of a planned dietary life skills course
Ida Ulrikke Valand,
Nina C Øverby,
Sofia Strömmer,
Mary Barker,
Camilla Bjornes,
Julie Nordli,
Line Pettersen,
Tormod Bjørkkjær,
Frøydis N Vik,
Charlotte Kiland,
& Elisabet R Hillesund
, 2022 , PLoS ONE , 17 (4 April)
DOI: 10.1371/journal.pone.0260890
Type: article
A capaciflector provides continuous and accurate respiratory rate monitoring for patients at rest and during exercise
Nick Hayward,
Mahdi Shaban,
James Badger,
Isobel Jones,
Yang Wei,
Daniel Spencer,
Stefania Isichei,
Martin Knight,
James Otto,
Gurinder Rayat,
Denny Levett,
Michael Grocott,
Harry Akerman,
& Neil White
, 2022 , Journal of Clinical Monitoring and Computing , 36 (5) , 1535--1546
DOI: 10.1007/s10877-021-00798-7
Type: article
Association of prenatal acetaminophen use and acetaminophen metabolites with DNA methylation of newborns: analysis of two consecutive generations of the Isle of Wight birth cohort
Shakiba Eslamimehr,
A Daniel Jones,
Thilani M Anthony,
S Hasan Arshad,
John W Holloway,
Susan Ewart,
Rui Luo,
Nandini Mukherjee,
Parnian Kheirkhah Rahimabad,
Su Chen,
& Wilfried Karmaus
, 2022 , Environmental Epigenetics , 8 (1) , dvac002
DOI: 10.1093/eep/dvac002
Type: article
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