Saul Nicholas Faust

Research

Research groups

Member of:

Research projects

Active projects

CiproPAL (Ciprofloxacin Prophylaxis in Acute Leukaemia): A randomised trial to assess the use of ciprofloxacin prophylaxis to prevent bacterial infection in children treated on the induction phase of the ALLTogether treatment protocol

Researchers:

Professor Saul Faust

Sponsor: National Institute of Health and Care Research

The PICBONE Study

Researchers:

Professor Saul Faust

Sponsor: National Institute of Health and Care Research

MISSION (Mid- Infrared Silicon Photonic Sensors for Healthcare and Environmental Monitoring)

Researchers:

Professor Graham Reed

Emeritus Professor James Wilkinson ,

Professor Senthil Murugan Ganapathy ,

Professor Saul Faust ,

Professor Goran Mashanovich ,

Doctor Milos Nedeljkovic

Sponsor: EPSRC

AGILE: Seamless Phase I/Iia Platform for the Rapid Evaluation of Candidates for COVID-19 treatment

Researchers:

Professor Gareth Griffiths

Professor Saul Faust

Sponsor: Medical Research Council

Using phages to give new life to old antibiotics against superbugs

Researchers:

Doctor Franklin Nobrega

Professor Saul Faust

Sponsor: Wessex Medical Research

NIHR Southampton Biomedical Research Centre 2017-2022

Researchers:

Professor Robert Read

Professor Chris Byrne ,

Professor Cyrus Cooper ,

Professor Philip Calder ,

Professor Ratko Djukanovic ,

Professor Keith Godfrey ,

Professor Hasan Arshad ,

Doctor Stephen Wootton ,

Professor Graham Roberts ,

Professor Saul Faust

Sponsor: National Institute of Health and Care Research

Safety And Immunogenicity Of Nasal Inoculation With Recombinant Neisseria Lactamica Expressing Factor H Binding Protein And Neisseria Adhesin A

Researchers:

Doctor Jay Laver

Professor Saul Faust ,

Professor Robert Read ,

Doctor Adam Dale

Sponsor: Medical Research Council

Completed projects

Prof Rosenberg Directors support

Researchers:

Professor Saul Faust

Sponsor: Wellcome Trust

Investigation of novel adjunctive therapies to improve treatment success in paediatric middle ear infection (otitis media)

Researchers:

Professor Saul Faust

Mr Rami Salib ,

Professor Jeremy Webb

Sponsor: Sparks Children's Medical Research Charity

Prof S Faust Wessex Medical Research M12

Researchers:

Professor Saul Faust

Sponsor: Wessex Medical Research

Dr Faust Meningitis Research 0613

Researchers:

Professor Saul Faust

Sponsor: Meningitis Research Foundation

PRo-adrenomedullin (MR-proADM) Evaluation of procalcitonin-guided antibiotic duration in Children with Infection for Stratification of Effectiveness (PRECISE)

Researchers:

Professor Saul Faust

Sponsor: National Institute of Health and Care Research

Biomarker-guided duration of antibiotic treatment in Children Hospitalised with confirmed or suspected bacterial infection

Researchers:

Professor Saul Faust

Sponsor: National Institute of Health and Care Research

Duration of INtravenous antibiOticc therapy for Septic arthritis or acUte osteomyelitis in a paediatRic population - DINOSAUR

Researchers:

Professor Saul Faust

Sponsor: National Institute of Health and Care Research

S Faust DoH: NISEC - 6 in 1 Hepatitis B virus vaccines

Researchers:

Professor Saul Faust

Professor Robert Read

Sponsor: National Institute of Health and Care Research

Prof R. Read: MRC Experimental Human Challenge with Genetically Modified Commensals to Investigate Respiratory Tract Mucosal Immunity and Colonisation

Researchers:

Professor Robert Read

Professor Ian Clarke ,

Professor Saul Faust

Sponsor: Medical Research Council

Prof R. Read: A genetically modified nasopharyngeal commensal as a platform for human bacteriotherapy

Researchers:

Professor Robert Read

Professor Ian Clarke ,

Professor Saul Faust

Sponsor: Medical Research Council

Laser-printable point of care sensors

Researchers:

Professor Saul Faust ,

Professor Peter Smith

Sponsor: EPSRC

Transmission Dynamics in Antimicrobial Resistance

Researchers:

Professor Jeremy Webb

Professor Saul Faust

Sponsor: Medical Research Council

The National Biofilms Innovation Centre

Researchers:

Professor Jeremy Webb

Professor Paul Stoodley ,

Professor Timothy Leighton ,

Professor Guy Baverstock-Poppy ,

Professor Saul Faust ,

Professor Charles Keevil ,

Doctor Callum Highmore ,

Doctor Joe Parker ,

Professor Jo Slater-Jefferies ,

Doctor Ivo Tews ,

Doctor Paulina Rakowska ,

Professor Peter Smith

An Integrated Systems Biology Approach to Bacterial Biofilm Development

Researchers:

Professor Jeremy Webb

Professor Stuart Clarke ,

Professor Saul Faust

Targeting Pneumococcal Carbohydrate Metabolism to Treat Childhood Infections

Researchers:

Doctor Claire Jackson ,

Professor Bruno Linclau ,

Professor Saul Faust ,

Professor Jeremy Webb

Sponsor: Rosetrees Trust

New Whole-Species Pneumococcal Biofilm Vaccines

Researchers:

Professor Jeremy Webb

Professor Saul Faust ,

Professor Stuart Clarke

Sponsor: Bill & Melinda Gates Foundation

Novel Pharmaceutical Agents (XF-drugs) to Prevent and Proactively Manage Bacterial Biofilm and Fungal Infections in Dynamic Model Systems

Researchers:

Professor Jeremy Webb

Professor Charles Keevil ,

Professor Saul Faust

Dr S Clarke - Bupa Carriage Sampling Methods

Researchers:

Professor Stuart Clarke

Professor Saul Faust ,

Emeritus Professor Michael Moore

Sponsor: BUPA Foundation

BioSci - Antabio Research Grant

Researchers:

Professor Jeremy Webb

Professor Saul Faust

Sponsor: Antabio

Dr M. Tebruegge: A Proteomic approach to the identification of novel biomarkers of tuberculosis

Researchers:

Professor Saul Faust ,

Professor Paul Skipp

Sponsor: Wessex Medical Research

Label-free Multimodal Imaging Platform for Detection of Biofilms

Researchers:

Professor Sumeet Mahajan

Professor Jeremy Webb ,

Professor Saul Faust

Low Dose Nitric Oxide for the Effective Treatment of Chronic Wounds

Researchers:

Professor Charles Keevil

Professor Jeremy Webb ,

Professor Saul Faust

Antabio 2 - Pseudomonas elastase inhibitors

Researchers:

Professor Jeremy Webb

Professor Saul Faust

Sponsor: Antabio

Southampton AMR Clinical Research Laboratory

Researchers:

Professor Robert Read

Emeritus Professor James Wilkinson ,

Professor Tristan Clark ,

Professor Hywel Morgan ,

Professor Saul Faust ,

Professor Jeremy Webb

Sponsor: National Institute of Health and Care Research

Personalised approach to Pseudomonas aeruginosa (PAPA)

Researchers:

Professor Jeremy Webb ,

Professor Saul Faust

Development of small molecule inhibitors of the Pseudomonas aeruginosa biofilms to treat chronic infections in cystic fibrosis patients. PHASE II.

Researchers:

Professor Jeremy Webb ,

Professor Saul Faust

Development of Small Molecule Inhibitors of the Pseudomonas aeruginosa Biofilms to Treat Chronic Infections in Cystic Fibrosis Patients. PHASE I.

Researchers:

Professor Jeremy Webb ,

Professor Saul Faust

Publications

271 publications

Page 1 of 28

The disease burden of respiratory syncytial virus in Infants

Alasdair P.S. Munro,

Federico Martinón-Torres,

Simon B. Drysdale,

& Saul N. Faust

, 2023 , Current opinion in infectious diseases , 36 (5) , 379--384

DOI: 10.1097/QCO.0000000000000952

Type: review

Higher dose corticosteroids in patients admitted to hospital with COVID-19 who are hypoxic but not requiring ventilatory support (RECOVERY)

Peter W. Horby,

Martin J. Landray,

Buddha Basnyat,

Saul Faust,

, 2023 , The Lancet , 401 (10387) , 1499--1507

DOI: 10.1016/S0140-6736(23)00510-X

Type: article

Adeno-associated virus 2 infection in children with non-A-E hepatitis

Antonia Ho,

Richard Orton,

Rachel Tayler,

Patawee Asamaphan,

Vanessa Herder,

Chris Davis,

Lily Tong,

Katherine Smollett,

Maria Manali,

Jay Allan,

Konrad Rawlik,

Sarah E McDonald,

Elen Vink,

Louisa Pollock,

Louise Gannon,

Clair Evans,

Jim McMenamin,

Kirsty Roy,

Kimberly Marsh,

Titus Divala,

Matthew T G Holden,

Michael Lockhart,

David Yirrell,

Sandra Currie,

Maureen O'Leary,

David Henderson,

Samantha J Shepherd,

Celia Jackson,

Rory Gunson,

Alasdair MacLean,

Neil McInnes,

Amanda Bradley-Stewart,

Richard Battle,

Jill A Hollenbach,

Paul Henderson,

Miranda Odam,

Primrose Chikowore,

Wilna Oosthuyzen,

Meera Chand,

Melissa Shea Hamilton,

Diego Estrada-Rivadeneyra,

Michael Levin,

Nikos Avramidis,

Erola Pairo-Castineira,

Veronique Vitart,

Craig Wilkie,

Massimo Palmarini,

Surajit Ray,

David L Robertson,

David Turner,

& Saul Faust

, 2023 , Nature , 617 (7961) , 555--563

DOI: 10.1038/s41586-023-05948-2

Type: article

Genomic investigations of unexplained acute hepatitis in children

Sofia Morfopoulou,

Sarah Buddle,

Oscar Enrique Torres Montaguth,

Laura Atkinson,

José Afonso Guerra-Assunção,

Mahdi Moradi Marjaneh,

Riccardo Zennezini Chiozzi,

Nathaniel Storey,

Luis Campos,

J. Ciaran Hutchinson,

John R. Counsell,

Gabriele Pollara,

Sunando Roy,

Cristina Venturini,

Juan F. Antinao Diaz,

Ala’a Siam,

Luke J. Tappouni,

Zeinab Asgarian,

Joanne Ng,

Killian S. Hanlon,

Alexander Lennon,

Andrew McArdle,

Agata Czap,

Joshua Rosenheim,

Catarina Andrade,

Glenn Anderson,

Jack C.D. Lee,

Rachel Williams,

Charlotte A. Williams,

Helena Tutill,

Nadua Bayzid,

Luz Marina Martin Bernal,

Hannah Macpherson,

Kylie Ann Montgomery,

Catherine Moore,

Kate Templeton,

Peter Simmonds,

Michael Carter,

Saul Faust,

Ruth Ensom,

Sarah Kelly,

Rebecca Jennings,

Michael Carter,

Anne McDonnell,

Emily Rowlands,

Luke Hodgson,

David Price,

Paul Whittaker,

Joanne Martin,

& Rachel Brown

, 2023 , Nature , 617 (7961) , 564--573

DOI: 10.1038/s41586-023-06003-w

Type: article

Psychological distress experienced by parents caring for an immunosuppressed child during the COVID-19 pandemic

Corine Driessens,

Lynne Mills,

Ravin Patel,

David Culliford,

Diane Gbesemete,

Emma Lee,

Meera Shanauk,

Harry Chappell,

Saul Faust,

& Hans De Graaf

, 2023 , Journal of Psychiatric Research , 161 , 273--281

DOI: 10.1016/j.jpsychires.2023.03.021

Type: article

Changes in paediatric pneumococcal carriage in Southampton UK during the SARS-CoV2 pandemic

David Cleary,

Jessica Jones,

James Campling,

Maria Lahuerta,

Kyla Hayford,

Jo Southern,

Brad D. Gessner,

Stephen D. Bentley,

Saul Faust,

& Stuart C. Clarke

, 2023

Type: conference

Comparative genomic epidemiology of serotype 3 IPD and carriage isolates from Southampton, UK between 2005 and 2017

David Cleary,

Stephanie W. Lo,

Narender Kumar,

Stephen D. Bentley,

Saul N. Faust,

& Stuart C. Clarke

, 2023 , Microbial Genomics , 9 (3)

DOI: 10.1099/mgen.0.000945

Type: article

Where now for infection services in the NHS? What about children?

Andrew Riordan,

Saul N Faust,

& Elizabeth Whittaker

, 2023 , Clinical Medicine , 23 (2) , 190--191

DOI: 10.7861/clinmed.Let.23.2.2

Type: article

Methylprednisolone versus intravenous immunoglobulins in children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS): an open-label, multicentre, randomised trial

Tatjana Welzel,

Andrew Atkinson,

Nina Schöbi,

Maya C. Andre,

Douggl G.N. Bailey,

Geraldine Blanchard-Rohner,

Michael Buettcher,

Serge Grazioli,

Henrik Koehler,

Marie Helene Perez,

Johannes Trück,

Federica Vanoni,

Petra Zimmermann,

Carlos Sanchez,

Julia A. Bielicki,

Luregn J. Schlapbach,

Andreas Bieri,

Spyridoula Gysi,

Indra Janz,

Birgit Donner,

Jürg Hammer,

Ulrich Heininger,

Malte Kohns Vasconcelos,

Nicole Mettauer,

Alexandra Meyer,

Diana Reppucci,

Chloé Schlaeppi,

Daniel Trachsel,

Nina Vaezipour,

Clemens von Kalckreuth,

Andreas Woerner,

Andreas Zutter,

Lisa Kottanattu,

Calogero Mazzara,

Alessia Severi Conti,

Christoph Aebi,

Philipp K.A. Agyeman,

Andrea Duppenthaler,

Martin Glöckler,

Sabine Pallivathukal,

Thomas Riedel,

Hong Phuc Cudré-Cung,

Mladen Pavlovic,

Alice Bordessoule,

Arnaud G. L'Huillier,

Anne Laure Martin,

Angelo Polito,

Marie Rohr,

Maria Isabel Rodriguez,

& Saul N. Faust

, 2023 , The Lancet Child & Adolescent Health , 7 (4) , 238--248

DOI: 10.1016/S2352-4642(23)00020-2

Type: article

Diagnosing acute bone and joint infection in children

Tim Theologis,

Mariea A. Brady,

Stuart Hartshorn,

Saul N. Faust,

& Amaka C. Offiah

, 2023 , The Bone & Joint Journal , 105-B (3) , 227--229

DOI: 10.1302/0301-620X.105B3.BJJ-2022-1179.R1

Type: article

External roles and responsibilities

Name: National Institute for Health Research Health Technology Assessment Programme (External organisation)

Role: Member

Year: 2016 -

Name: NICE Public Health (External organisation)

Role: Chair

Year: 2014 - 2016

Name: NICE Public Health (External organisation)

Role: Chair

Year: 2016 - 2018

Name: NHS England National Commissioning Paediatric Medicine Clinical Reference Group (External organisation)

Role: Member

Year: 2013 - 2022

Name: UK NIHR Paediatric Theme Clinical Speciality Group Chair’s Forum (External organisation)

Role: Chair

Year: 2013

Name: South of England and National Paediatric Immunology & Infectious Diseases (External organisation)

Role: Chair

Year: 2013

Name: South of England and National Paediatric Immunology & Infectious Diseases (External organisation)

Role: Member

Year: 2016

Name: South of England and National Paediatric Immunology & Infectious Diseases (External organisation)

Role: Member

Year: 2019 - 2022

Name: European Medicines Agency (External organisation)

Role: Chair

Year: 2013 - 2017

Name: UK NIHR Paediatric Theme Clinical Speciality Group Chair’s Forum (External organisation)

Role: Chair

Year: 2011

Professor Saul Faust

Connect with Saul

Research

Research groups

Research projects

Active projects

Completed projects

Publications

External roles and responsibilities

Biography