Research project

Prof S. Khakoo: Peptide antagonism and NK cell activation: mechanism and relevance

Lead researcher:

Professor Salim Khakoo
Research funder:

Medical Research Council
Status:

Not active

Staff

Lead researcher

Professor Salim Khakoo

Professor of Hepatology

Email: s.i.khakoo@soton.ac.uk

Research outputs

IL-12 and IL-15 induce the expression of CXCR6 and CD49a on peripheral natural killer cells

Theresa Hydes,

Angela Noll,

Gabriela Salinas-Riester,

Mohammad Abu Hilal,

Thomas Armstrong,

Zaed Hamady,

John Primrose,

Arjun Takhar,

Lutz Walter,

& Salim Khakoo

, 2018 , Immunity, Inflammation and Disease , 6 (1) , 34--36

DOI: 10.1002/iid3.190

Type: article

Fine-mapping of genetic loci driving spontaneous clearance of hepatitis C virus infection

Hailiang Huang,

Priya Duggal,

Chloe L. Thio,

Rachel Latanich,

James J. Goedert,

Alessandra Mangia,

Andrea L. Cox,

Gregory D. Kirk,

Shruti Mehta,

Jasneet Aneja,

Laurent Alric,

Sharyne M. Donfield,

Matthew E. Cramp,

Salim Khakoo,

Leslie H. Tobler,

Michael Busch,

Graeme J. Alexander,

Hugo R. Rosen,

Brian R. Edlin,

Florencia P. Segal,

Georg M. Lauer,

David L. Thomas,

Mark J. Daly,

Raymond T. Chung,

& Arthur Y. Kim

, 2017 , Scientific Reports , 7 , 1--9

DOI: 10.1038/s41598-017-16011-2

Type: article

HLA-Bw4 80(T) and multiple HLA-Bw4 copies combined with KIR3DL1 associate with spontaneous clearance of HCV infection in people who inject drugs

Christine Thöns,

Tina Senff,

Theresa J. Hydes,

Angela R. Manser,

Falko M. Heinemann,

Andreas Heinold,

Martin Heilmann,

Arthur Y. Kim,

Markus Uhrberg,

Norbert Scherbaum,

Georg M. Lauer,

Salim I. Khakoo,

& Jörg Timm

, 2017 , Journal of Hepatology , 67 (3) , 462--470

DOI: 10.1016/j.jhep.2017.03.040

Type: article

KIR2DS2 recognizes conserved peptides derived from viral helicases in the context of HLA-C

Mohammed M. Naiyer,

Sorcha A. Cassidy,

Andrea Magri,

Vanessa Cowton,

Kevin Chen,

Salah Mansour,

Hariklia Kranidioti,

Berenice Mbiribindi ,

Pauline Rettman,

Scott Harris,

Liam J. Fanning,

Arend Mulder,

Franz H.J. Claas,

Andrew D. Davidson,

Arvind H. Patel,

Marco A. Purbhoo,

& Salim I. Khakoo

, 2017 , Science immunology , 2 (15)

DOI: 10.1126/sciimmunol.aal5296

Type: article

A vision of KIR variation at super resolution

J.A. Hammond,

M. Carrington,

& S.I. Khakoo

, 2016 , Immunology , 1--9

DOI: 10.1111/imm.12606

Type: article