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Research project

The Immune Regulation of Macrophage Antibody Dependent Cellular Phagocytosis

Staff

Lead researcher

Professor Mark Cragg

Professor in Experimental Cancer Biology

Research interests

  • Antibody biology
  • Antibody engineering

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Other researchers

Doctor Stephen Thirdborough

Senior Research Fellow

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Professor Stephen Beers

Professor of Immunology & Immunotherapy

Research interests

  • Edit
  • Antibody Effector Functions Monoclonal antibodies (mAb) have become established in the treatment of a variety of malignancies - transforming patient outcomes. Despite this undoubted impact, responses remain variable and their mechanisms of action and of tumour resistance are controversial. Our research is focussed on understanding these complex processes using a variety of complementary models and systems to better inform antibody selection, design and clinical application.

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Collaborating research institutes, centres and groups

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