Professor Ronan McCarthy

Publications

29 publications

Page 3 of 3

Ronan R McCarthy, Muhammad Wajid Ullah, Eujin Pei & Guang Yang, 2019, Trends in Biotechnology, 37(11), 1155-1159

DOI: 10.1016/j.tibtech.2019.05.004

Type: article

Cyclic di-GMP inactivates T6SS and T4SS activity in agrobacterium tumefaciens

Ronan R McCarthy, Manda Yu, Kira Eilers, Yi-Chieh Wang, Erh-Min Lai & Alain Filloux, 2019, Molecular Microbiology, 112(2), 632-648

DOI: 10.1111/mmi.14279

Type: article

Head start immunity

Ronan R McCarthy, Helen E Everett, Simon P Graham, Falko Steinbach & Helen R Crooke, 2019, Frontiers in Immunology, 10, 1584

DOI: 10.3389/fimmu.2019.01584

Type: article

Quorum sensing signaling alters virulence potential and population dynamics in complex microbiome-host interactomes

F Jerry Reen, José A Gutiérrez-Barranquero, Ronan R McCarthy, David F Woods, Sara Scarciglia, Claire Adams, Kristian Fog Nielsen, Lone Gram & Fergal O'Gara, 2019, Frontiers in Microbiology, 10, 2131

DOI: 10.3389/fmicb.2019.02131

Type: article

Cyclic-di-GMP regulates lipopolysaccharide modification and contributes to Pseudomonas aeruginosa immune evasion

Ronan R McCarthy, Maria J Mazon-Moya, Joana A Moscoso, Youai Hao, Joseph S Lam, Christophe Bordi, Serge Mostowy & Alain Filloux, 2017, Nature Microbiology, 2, 17027

DOI: 10.1038/nmicrobiol.2017.27

Type: article

Contribution of cyclic di-GMP in the control of type III and type VI secretion in pseudomonas aeruginosa

Ronan R McCarthy, Martina Valentini & Alain Filloux, 2017, Methods in molecular biology (Clifton, N.J.), 1657, 213-224

DOI: 10.1007/978-1-4939-7240-1_17

Type: article

Direct detection of lipid A on intact Gram-negative bacteria by MALDI-TOF mass spectrometry

Gerald Larrouy-Maumus, Abigail Clements, Alain Filloux, Ronan R McCarthy & Serge Mostowy, 2015, Journal of Microbiological Methods, 120, 68-71

DOI: 10.1016/j.mimet.2015.12.004

Type: article

Deciphering the role of coumarin as a novel quorum sensing inhibitor suppressing virulence phenotypes in bacterial pathogens

José A Gutiérrez-Barranquero, F Jerry Reen, Ronan R McCarthy & Fergal O'Gara, 2015, Applied Microbiology and Biotechnology, 99(7), 3303-16

DOI: 10.1007/s00253-015-6436-1

Type: article

A new regulator of pathogenicity (bvlR) is required for full virulence and tight microcolony formation in Pseudomonas aeruginosa

Ronan R McCarthy, Marlies J Mooij, F Jerry Reen, Olivier Lesouhaitier & Fergal O'Gara, 2014, Microbiology (Reading, England), 160(Pt 7), 1488-1500

DOI: 10.1099/mic.0.075291-0

Type: article

Biography

Ronan gained his Bachelor of Science in Genetics with first class honours from University College Cork, Ireland in 2010 and was awarded the title of College Scholar. In autumn 2010, Ronan was awarded an Irish Research Council PhD Scholarship to study novel biofilm inhibition strategies against the opportunistic pathogen Pseudomonas aeruginosa in the lab of Professor Fergal O’Gara. In 2014, Ronan joined the research group of Professor Alain Filloux at the MRC Centre for Bacteriology and Infection at Imperial College London. As a Postdoctoral Research Associate, Ronan interrogated the second messenger signalling cascades that govern the biofilm mode of growth in Pseudomonas aeruginosa and Agrobacterium tumefaciens. Following on from his time at Imperial College Ronan joined the Microbiology Department at the Animal and Plant Health Agency where he used host transcriptomics and pathway analysis to profile the host response to infection. He joined the Biosciences Division in Brunel University to continue his analysis of the regulatory networks that govern pathogenicity, antimicrobial resistance and biofilm formation in the Gram negative opportunistic pathogens Pseudomonas aeruginosa and Acinetobacter baumannii. In 2021, Ronan was awarded a BBSRC New Investigator Award to study the regulation of desiccation tolerance and biofilm formation in Acinetobacter baumannii and to identify compounds that could disrupt these survival mechanisms. He has also expanded into the field of biofilm engineering, using synthetic biology approaches to give control over bacterial biofilm formation and using these tools to tackle environmental challenges such as plastic waste. As a PI he has secured funding from the BBSRC, NC3Rs, Academy of Medical Sciences, Horizon 2020, British Society for Antimicrobial Chemotherapy, Innovate UK, NERC and the Medical Research Council. In 2025, he joined the University of Southampton to continue his work on understanding, harnessing and disrupting the regulatory pathways that govern biofilm formation.

Connect with Ronan

Publications

Biography