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Research project

Computational modelling to evaluate, understand and predict the placental transfer of xenobiotics as an integrated system

Staff

Lead researchers

Dr Bram Sengers

Associate Professor
Connect with Bram

Email: B.G.Sengers@soton.ac.uk

Other researchers

Professor Xunli Zhang PhD, DIC, FRSC, CChem, CEng

Professor of Bioengineering
Research interests
  • Microfluidics and Lab-on-a-Chip Technologies
  • Biomedical and Chemical Engineering
  • Nanomaterials
Connect with Xunli

Email: XL.Zhang@soton.ac.uk

Professor Rohan Lewis PhD, FTPS

Prof of Placental&Integrative Physiology
Connect with Rohan

Email: Rohan.Lewis@soton.ac.uk

Dr Jane Cleal PhD

Associate Professor
Research interests
  • Areas of Scientific Expertise:
  • Reproductive Cell Biology – Fundamental mechanisms of cell biology in placenta and endometriu…
Connect with Jane

Email: J.K.CLEAL@soton.ac.uk

Research outputs

A systems perspective on placental amino acid transport
Jane K. Cleal, Emma M. Lofthouse, Bram G. Sengers & Rohan M. Lewis, 2018, The Journal of Physiology, 596(23), 5511-5522
DOI: 10.1113/JP274883
Type: review
Estrone sulphate uptake by the microvillous membrane of placental syncytiotrophoblast is coupled to glutamate efflux
Emma M Lofthouse, Jane K Cleal, Ita M O'Kelly, Bram G Sengers & Rohan M Lewis, 2018, Biochemical and Biophysical Research Communications
DOI: 10.1016/j.bbrc.2018.10.074
Type: article