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Doctor Jane Cleal

Dr Jane Cleal

Associate Professor

Research interests

  • Areas of Scientific Expertise:
  • Reproductive Cell Biology – Fundamental mechanisms of cell biology in placenta and endometrium and the impact on the intra-uterine environment, fetal development and lifelong health.Regulation of Reproductive Cell Biology – Maternal exposures and molecular regulation of cellular gene expression, phenotype and function in placenta and endometrium and the clinical translation.Disease/phenotype – Fetal growth, Obesity, Cardiometabolic programming, Subfertility, Recurrent pregnancy loss.Cellular mechanisms – Membrane transport, endocytosis, vesicular transport & signalling, gene transcription, microRNA biology, epigenetic regulation.Vitamin D - Transport, regulation, metabolism and signalling.

More research

Accepting applications from PhD students.

Connect with Jane


Dr Jane Cleal is a lecturer in Reproductive Cell Biology in the Faculty of medicine at the University of Southampton.

‘My research investigates the molecular mechanisms that regulate the placenta and maternal tissues during pregnancy so as to translate the findings into interventions to improve pregnancy outcome and fetal growth.’

Dr Cleal was appointed to her current post as a lecturer in the FoM in 2010. She leads a research team integrating whole systems biology with cellular and molecular mechanisms in relation to fundamental developmental physiology, reproductive and pregnancy disorders (see Research pages) and collaborates with a number of national and international researchers. She is a committee member on several panels including the BBSRC and International Workshop for Vitamin D.

Dr Cleal’s interfaculty education roles span undergraduate and postgraduate programmes for the Faculties of Medicine and Environmental & Life Sciences and include Deputy Programme lead for the BM6 widening access to medicine degree (see Teaching section). Her outreach activities introduce both the public and school children to reproductive science and making healthy life choices.