Staff

Lead researchers

Professor Ian Sinclair

Professor of Engineering Materials
Connect with Ian

Email: I.Sinclair@soton.ac.uk

Other researchers

Professor Simon Coles

Professor of Structural Chemistry
Research interests
  • The work we do is highly collaborative and multidisciplinary and can broadly be split into three overlapping themes:
  • 1) National Crystallography Service (NCS, www.ncs.ac.uk) & Physical Sciences Data-science Service (PSDS, www.psds.ac.uk) These national centres provide centralised facilities for UK researchers at a level that is beyond that achievable in any single institution. The NCS provides data collection and crystal structure analysis for the UK chemistry community. It also performs projects based on more advanced techniques, involving a dedicated team of experts employing cutting edge techniques and the use of very high-powered laboratory diffractometers or the UK synchrotron, Diamond. The PSDS provides national-level access to databases and is building infrastructure on top of these to drive and support data-driven approaches to scientific discovery.
  • 2) Structural Chemistry We have an interest in determining the mechanisms of solid-state reactions and transformations and use a variety of diffraction and physical characterisation methods for this. Other work focuses on discovering and investigating structure-property relationships, the determination of charge densities and their properties and 'value-added' quantum mechanical calculations to compute properties from crystal structures. We also collaborate with other disciplines in a number of areas such as macromolecular crystallography (Biology), crystal growth (biology) and CT imaging (Engineering).
Connect with Simon

Email: S.J.Coles@soton.ac.uk

Emeritus Professor Richard Oreffo DPhil DSc (Oxon) FMedSci FHEA FRSB FIOR

Research interests
  • Skeletal Regenerative MedicineSkeletal Stem Cells
Connect with Richard

Email: Richard.Oreffo@soton.ac.uk

Professor Mark Spearing

Vice-President (Research & Enterprise)
Connect with Mark

Email: S.M.Spearing@soton.ac.uk

Emeritus Professor Chris Clayton

Connect with Chris

Email: C.Clayton@soton.ac.uk

Professor Jeremy Frey

Professor of Physical Chemistry
Connect with Jeremy

Email: J.G.Frey@soton.ac.uk

Emeritus Professor Mark Nixon

Research interests
  • My research interests are in image processing and computer vision.
  • I have helped to develop new techniques for static and moving shape extraction (both parametric and non-parametric) which have found application in automatic face and automatic gait recognition and in medical image analysis.
Connect with Mark

Email: msn@ecs.soton.ac.uk

Collaborating research institutes, centres and groups

Research outputs

High-resolution 3D imaging of osteocytes and computational modelling in mechanobiology: Insights on bone development, ageing, health and disease
Patricia Goggin, Konstantinos Zygalakis, Richard Oreffo & Philipp Schneider, 2016, European Cells & Materials, 31, 264-295
DOI: 10.22203/eCM.v031a18
Type: article
Three-dimensional characterization of fibroblast foci in idiopathic pulmonary fibrosis
Mark G. Jones, Aurélie Fabre, Philipp Schneider, Francesco Cinetto, Giacomo Sgalla, Mark Mavrogordato, Sanjay Jogai, Aiman Alzetani, Ben G. Marshall, Katherine M.A. O'Reilly, Jane A. Warner, Peter M. Lackie, Donna E. Davies, David M. Hansell, Andrew G. Nicholson, Ian Sinclair, Kevin K. Brown & Luca Richeldi, 2016, JCI Insight, 1(5)
DOI: 10.1172/jci.insight.86375
Type: article
Imaging the interaction of roots and phosphate fertiliser granules using 4D X-ray tomography
Sharif Ahmed, Trudy Naugler Klassen, Samuel Keyes, Michael Daly, David L. Jones, Mark N. Mavrogordato, Ian Sinclair & Tiina Roose, 2016, Plant and Soil, 401(1), 125-134
DOI: 10.1007/s11104-015-2425-5
Type: article
Struvite: a slow-release fertiliser for sustainable phosphorus management
Peter J. Talboys, James Heppell, Jessica Daniel, Tiina Roose, John Healey, Davey L. Jones & Paul J.A. Withers, 2016, Plant and Soil, 401(1), 109-123
DOI: 10.1007/s11104-015-2747-3
Type: article
Image based modeling of nutrient movement in and around the rhizosphere
K.R. Daly, S.D. Keyes, S. Masum & T. Roose, 2016, Journal of Experimental Botany, 1-12
DOI: 10.1093/jxb/erv544
Type: article