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Research project

Establishment of a National Network on Musculoskeletal Ageing

Staff

Lead researchers

Professor Cyrus Cooper

Prof Rheumatology Clinical Epidemiology
Research interests
  • Key research contributions have been:
  • discovery of the developmental influences which contribute to the risk of osteoporosis and hip fracture in late adulthood
  • demonstration that maternal vitamin D insufficiency is associated with sub-optimal bone mineral accrual in childhood
Connect with Cyrus

Email: cc@mrc.soton.ac.uk

Other researchers

Professor Nicholas Harvey

Director/Professor
Research interests
  • Lifecourse epidemiology of osteoporosis and fragility fractures
  • Understanding mechanism and development of novel interventions across lifecourse to prevent fragility fractures
Connect with Nicholas

Email: nch@mrc.soton.ac.uk

Collaborating research institutes, centres and groups

Research outputs

Menopausal hormone therapy reduces the risk of fracture regardless of falls risk or baseline FRAX probability - results from the Women's Health Initiative hormone therapy trials
Mattias Lorentzen, Helena Johansson, Nicholas Harvey, Enwu Liu, Liesbeth Vandenput, Carolyn J. Crandall, Jane A. Cauley, Meryl S. LaBoff, E.V. McCloskey & John A. Kanis, 2022, Osteoporosis International, 33(11), 2297-2305
DOI: 10.1007/s00198-022-06483-y
Type: article
Role of Vitamin D supplementation in the management of musculoskeletal diseases: update from an European Society of Clinical and Economical Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) working group
Thierry Chevalley, M.L. Brandi, Kevin D. Cashman, Etienne Cavalier, Nicholas Harvey, Stefania Maggi, Cyrus Cooper, Nasser M. Al-Daghri, Oliver Bock, Olivier Bruyère, Mario M. Rosa, B. Cortet, Alfonso Jose Cruz-Jentoft, Antonio Cherubini, Bess Dawson-Hughes, Roger A. Fielding, Nicholas Fuggle, Philippe Halbout, John A. Kanis, J.M. Kaufman, Olivier Lamy, Andrea Laslop, María Concepción  Prieto Yerro, Regis Pierre Rademecker, Jotheeswaran Amuthavalli Thiyagarajan, Thierry Thomas, Nicola Veronese, Marten de Wit, Jean Yves Reginster & Rene Rizzoli, 2022, Aging Clinical and Experimental Research, 34(11), 2603-2623
DOI: 10.1007/s40520-022-02279-6
Type: review
Cardiovascular disease and mortality sequelae of COVID-19 in the UK Biobank
Zahra Raisi-Estabragh, Jackie Cooper, Ahmed Salih, Betty Raman, Aaron Mark Lee, Stefan Neubauer, Nicholas C Harvey & Steffen E Petersen, 2022, Heart, 109(2), 119-126
DOI: 10.1136/heartjnl-2022-321492
Type: article
Impact of the COVID-19 pandemic on community-dwelling older adults
Ilse Bloom, Jean Zhang, Julia Hammond, Gregorio Bevilacqua, Wendy Lawrence, Kate A Ward, Cyrus Cooper & Elaine M Dennison, 2022, PLoS ONE, 17(10 October)
DOI: 10.1371/journal.pone.0275486
Type: article
Osteoporosis treatment in Austria-assessment of FRAX-based intervention thresholds for high and very high fracture risk
Hans P. Dimai, Helena Johansson, Nicholas C. Harvey, Mattias Lorentzon, Enwu Liu, Liesbeth Vandenput, Astrid Fahrleitner-Pammer, Peter Pietschmann, Christian Muschitz, Eugene V. McCloskey & John A. Kanis, 2022, Archives of Osteoporosis, 17(1)
DOI: 10.1007/s11657-022-01175-w
Type: article
General comorbidity indicators contribute to fracture risk independent of FRAX
Gregory A Kline, Suzanne N Morin, Lisa M Lix, Eugene V McCloskey, Helena Johansson, Nicholas C. Harvey, John A Kanis & William D Leslie, 2022, Journal of Clinical Endocrinology & Metabolism
DOI: 10.1210/clinem/dgac582
Type: article
Effect of discordant hip bone density on incident fracture risk
William D. Leslie, Suzanne N. Morin, Lisa M. Lix, Eugene V. McCloskey, Helena Johansson, Nicholas C. Harvey & John A. Kanis, 2022, Journal of Bone and Mineral Research, 37(10), 2018-2024
DOI: 10.1002/jbmr.4672
Type: article