Establishment of a National Network on Musculoskeletal Ageing

Staff

Lead researcher

Professor Cyrus Cooper

Prof Rheumatology Clinical Epidemiology

Research interests

Key research contributions have been:
discovery of the developmental influences which contribute to the risk of osteoporosis and hip fracture in late adulthood
demonstration that maternal vitamin D insufficiency is associated with sub-optimal bone mineral accrual in childhood

Connect with Cyrus

Email: cc@mrc.soton.ac.uk

Other researchers

Professor Nicholas Harvey

Director/Professor

Research interests

Lifecourse epidemiology of osteoporosis and fragility fractures
Understanding mechanism and development of novel interventions across lifecourse to prevent fragility fractures

Connect with Nicholas

Email: nch@mrc.soton.ac.uk

Collaborating research institutes, centres and groups

Interdisciplinary Musculoskeletal Health

The University hosts a substantial interdisciplinary community of researchers working to transform musculoskeletal health across the life course.

Research outputs

Menopausal hormone therapy reduces the risk of fracture regardless of falls risk or baseline FRAX probability - results from the Women's Health Initiative hormone therapy trials

Mattias Lorentzen,

Helena Johansson,

Nicholas Harvey,

Enwu Liu,

Liesbeth Vandenput,

Carolyn J. Crandall,

Jane A. Cauley,

Meryl S. LaBoff,

E.V. McCloskey,

& John A. Kanis

, 2022 , Osteoporosis International , 33 (11) , 2297--2305

DOI: 10.1007/s00198-022-06483-y

Type: article

Update of the fracture risk prediction tool FRAX: A systematic review of potential cohorts and analysis plan

Lisbeth Vandenput,

H. Johansson,

E. V. McCloskey,

E. Liu,

Kristina E. Akesson,

F.A. Anderson,

R. Azagra,

C.L. Bager,

Charlotte Beaudart,

H.A. Bischoff-Ferrari,

E. Biver,

Olivier Bruyère,

J.A. Cauley,

J.R. Center,

R. Chapulat,

C. Christiansen,

Cyrus Cooper,

Carolyn J. Crandall,

Steven Cummings,

J.A.P. da Silva,

Bess Dawson-Hughes,

A. Diez-Pérez,

Alyssa B. Dufour,

J.A. Eisman,

Petra J.M. Elders,

S. Ferrari,

Y. Fujita,

S. Fujiwara,

C.C. Glüer,

I. Goldstein,

D. Goltzman,

V. Gudnason,

J. Hall,

D. Hans,

M. Hoff,

Rosemary J. Hollick,

Martijn Huisman,

M. Iki,

S. Ish-Shalom,

G. Jones,

M.K. Karlsson,

Sundeep Khosla,

D.P. Kiel,

W-P Koh,

F. Koromani,

M.A. Kotowicz,

H. Kroger,

T. Kwok,

Olivier Lamy,

Arnulf Langhammer,

Bagher Larijani,

Kurt Lippuner,

D Mellström,

Thomas Merlijn,

A. Nordstrom,

P. Nordstrom,

T.W. O'Neill,

B. Obermayer-Piestch,

Nicholas Harvey,

J A. Kanis,

C. Ohlsson,

E.S. Orwoll,

J.A. Pasco,

F. Rivadeneira,

B. Schei,

A.M. Schott,

E.J. Shiroma,

K. Siggeirsdottir,

E.M. Simonsick,

E. Sornay-Rendu,

R. Sund,

K.M.A. Swart,

P. Szulc,

J. Tamaki,

D.J. Torgerson,

N.M. Van Schoor,

T.P. van Staa,

J.C. Vilas,

N.J Wareham,

N.C. Wright,

N. Yoshimura,

M.C. Zillikens,

M. Zwart,

M. Lorentzon,

& W.D. Leslie

, 2022 , Osteoporosis International , 33 (10) , 2103--2136

DOI: 10.1007/s00198-022-06435-6

Type: review

Quantitating age-related BMD textural variation from DXA region-free-analysis: a study of hip fracture prediction in three cohorts

Mohsen Farzi,

Jose M. Pozo,

Eugene McCloskey,

Richard Eastell,

Nicholas Harvey,

Alejandro Frangi,

& Jeremy Mark Wilkinson

, 2022 , Journal of Bone and Mineral Research , 37 (9) , 1679--1688

DOI: 10.1002/jbmr.4638

Type: article

Nutritional risk and its relationship with physical function in community-dwelling older adults

Ilse Bloom,

Jean Zhang,

Camille Parsons,

Gregorio Bevilacqua,

Elaine Dennison,

Cyrus Cooper,

& Kate Ward

, 2022 , Aging Clinical and Experimental Research , 34 (9) , 2031--2039

DOI: 10.1007/s40520-022-02171-3

Type: article

Is it time to consider population screening for fracture risk in postmenopausal women? A position paper from the International Osteoporosis Foundation Epidemiology/Quality of Life Working Group.

Pojchong Chotiyarnwong,

E. V. McCloskey,

Nicholas Harvey,

M. Lorentzon,

Daniel Prieto-Alhambra,

B. Abrahamsen,

J.D Adachi,

F. Borgström,

Olivier Bruyère,

J J Carey,

P. Clark,

Cyrus Cooper,

Elizabeth Curtis,

Elaine Dennison,

Manuel Diaz Curiel,

H.P. Dimai,

D. Grigorie,

Mickaël Hiligsmann,

Patricia Khashayar,

E. Michael Lewiecki,

P. Lips,

R.S. Lorenc,

S. Ortolani,

A. Papaioannou,

S. Silverman,

Manuel Sosa-Henríquez,

Pawel Szulc,

Kate Ward,

N. Yoshimura,

& J A. Kanis

, 2022 , Archives of Osteoporosis , 17 (1)

DOI: 10.1007/s11657-022-01117-6

Type: article