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Research project

Hanson RG/15/17/31749 Epigenetic Biomarkers and Determinants of Cardiovascular Risk in Children

Staff

Lead researcher

Emeritus Professor Mark Hanson

Other researchers

Professor Cyrus Cooper

Prof Rheumatology Clinical Epidemiology

Research interests

  • Key research contributions have been:
  • discovery of the developmental influences which contribute to the risk of osteoporosis and hip fracture in late adulthood
  • demonstration that maternal vitamin D insufficiency is associated with sub-optimal bone mineral accrual in childhood

Professor Keith Godfrey

Associate Dean Enterprise

Professor Karen Lillycrop

Professor of Epigenetics

Research interests

  • Epigenetics
  • Human Disease

Emeritus Professor Hazel Inskip MSc, PhD, FFPH

Collaborating research institutes, centres and groups

Plants and Food Security

We study the response of plants to the environment at the molecular, whole plant and ecological levels. This includes interactions with nematodes, insects and microbes.

Research outputs

High placental inositol content associated with suppressed pro-adipogenic effects of maternal glycaemia in offspring
Anne H.Y. Chu,
Rohan Lewis,
& Keith Godfrey
, 2021 , International Journal of Obesity , 45 (1) , 247--257
DOI: 10.1038/s41366-020-0596-5
Type: article
Adiposity associated DNA methylation signatures in adolescents are related to leptin and perinatal factors
R.C. Huang,
P.E. Melton,
M.A. Burton,
L.J. Beilin,
R. Clarke-Harris,
E. Cook,
K.M. Godfrey,
G.C. Burdge,
T.A. Mori,
D Anderson ,
S. Rauschert,
J.M. Craig,
M.S. Kobor,
J.L. MacIsaac,
A.M. Morin,
W.H. Oddy,
C.E. Pennell,
J.D. Holbrook,
& K.A. Lillycrop
, 2021 , Epigenetics
DOI: 10.1080/15592294.2021.1876297
Type: article
Characterising and monitoring preconception health in England: a review of national population-level indicators and core data sources
Danielle Schoenaker,
Judith Stephenson,
Anne Connolly,
Sally Shillaker,
Sarah Fishburn,
Mary Barker,
Keith Godfrey,
& Nisreen Alwan
, 2021 , Journal of Developmental Origins of Health and Disease
DOI: 10.1017/S2040174421000258
Type: article
Childhood DNA methylation as a marker of early life rapid weight gain and subsequent overweight
N. Robinson,
H. Brown,
Elie Antoun,
Keith Godfrey,
Mark Hanson,
Karen Lillycrop,
Sarah Crozier,
Robert Murray,
M.S. Pearce,
C.L. Relton,
V. Albani,
& J.A. McKay
, 2021 , Clinical Epigenetics , 13 (1)
DOI: 10.1186/s13148-020-00952-z
Type: article
DNA methylation signatures in cord blood associated with birthweight are enriched for dmCpGs previously associated with maternal hypertension or pre-eclampsia, smoking and folic acid intake
Elie Antoun,
Philip Titcombe,
Kathryn V. Dalrymple,
Negusse Kitaba,
Sheila Barton,
A.C. Flynn,
Robert Murray,
Emma Garratt,
Paul T. Seed,
Sara L. White,
Cyrus Cooper,
Hazel Inskip,
Mark Hanson,
L. Poston,
Keith Godfrey,
& Karen Lillycrop
, 2021 , Epigenetics
DOI: 10.1080/15592294.2021.1908706
Type: article