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Research project

Hanson RG/15/17/31749 Epigenetic Biomarkers and Determinants of Cardiovascular Risk in Children

Staff

Lead researcher

Emeritus Professor Mark Hanson

Other researchers

Professor Cyrus Cooper

Prof Rheumatology Clinical Epidemiology

Research interests

  • Key research contributions have been:
  • discovery of the developmental influences which contribute to the risk of osteoporosis and hip fracture in late adulthood
  • demonstration that maternal vitamin D insufficiency is associated with sub-optimal bone mineral accrual in childhood

Professor Keith Godfrey

Associate Dean Enterprise

Professor Karen Lillycrop

Professor of Epigenetics

Research interests

  • Epigenetics
  • Human Disease

Emeritus Professor Hazel Inskip MSc, PhD, FFPH

Collaborating research institutes, centres and groups

Plants and Food Security

We study the response of plants to the environment at the molecular, whole plant and ecological levels. This includes interactions with nematodes, insects and microbes.

Research outputs

Maternal glycemia during pregnancy and child carotid intima media thickness, pulse wave velocity, and augmentation index
Wen Lun Yuan,
J. Lin,
Michael S. Kramer,
Keith Godfrey,
Peter D. Gluckman,
Yap-Seng Chong,
Lynette P. Shek,
Kok Hian Tan,
Shiao-Yng Chan,
Johan G. Eriksson,
Fabian Yap,
Yung Seng Lee,
Jonathan T.L. Choo,
& L.H. Ling
, 2020 , Journal of Clinical Endocrinology & Metabolism , 105 (7) , 1--10
DOI: 10.1210/clinem/dgaa211
Type: article
Mismatch between poor fetal growth and rapid postnatal weight gain in the first 2 years of life Is associated with higher blood pressure and insulin resistance without increased adiposity in childhood: The GUSTO Cohort Study
Yi Ying Ong,
Suresh Anand Sadananthan,
Izzuddin M. Aris,
Mya Thway Tint,
Wen Lun Yuan,
Jonathan Y. Huang,
Yiong Huak Chan,
Sharon Ng,
See Ling Loy,
Sendhil Velan,
Marielle V. Fortier,
Keith Godfrey,
Lynette Shek,
Kok Hian Tan,
Peter D. Gluckman,
Fabian Yap,
Jonathan Tze Liang Choo,
Lieng Hsi Ling,
Karen Tan,
Li Chen,
Neerja Karnani,
Yap-Seng Chong,
Johan G. Eriksson,
Mary E. Wlodek,
Shiao-Yng Chan,
Yung Seng Lee,
& Navin Michael
, 2020 , International Journal of Epidemiology , 49 (5)
DOI: 10.1093/ije/dyaa143
Type: article
Eating behaviors moderate the associations between risk factors in the first 1,000 days and adiposity outcomes at 6 years of age
Anna Fogel,
Keri McCrickerd,
Izzuddin M. Aris,
Ai Ting Goh,
Yap-Seng Chong,
Kok Hian Tan,
Fabian Yap,
Lynette P. Shek,
Michael J. Meaney,
Birit F.P. Broekman,
Keith Godfrey,
Mary Foong-Fong Chong,
Shirong Cai,
Wei Wei Pang,
Wen Lun Yuan,
Yung Seng Lee,
& Ciaran G Forde
, 2020 , American Journal of Clinical Nutrition , 997--1006
DOI: 10.1093/ajcn/nqaa052
Type: article
Anthropometric measures and HbA1c to detect dysglycemia in young Asian women planning conception: The S-PRESTO cohort
Anne H.Y. Chu,
I.M. Aris,
Sharon Ng,
Jonathan Y. Bernard,
Tint Mya,
Wen Lun Yuan,
Keith Godfrey,
Jerry Kok Yen Chan,
Lynette P. Shek,
Yap-Seng Chong,
K.H. Tan,
Seng Bin Ang,
H.H. Tan,
Bernard SM Chern,
Fabian Yap,
Yung Seng Lee,
Ngee Lek,
Melvin Khee-Shing Leow,
Chin Meng Khoo,
& Shiao-Yng Chan
, 2020 , Scientific Reports , 10 (1)
DOI: 10.1038/s41598-020-66147-x
Type: article
Developmental origins of health and disease: impact of environmental dust exposure in modulating microbiome and its association with non-communicable diseases
Delicia Shu-Qin Ooi,
Cheryl Pei-Ting Tan,
Michelle Jia-Yu Tay,
Siong Gim Ong,
Elizabeth Huiwen Tham,
Kewin Tien Ho Siah,
Johan Gunnar Eriksson,
Keith Godfrey,
Lynette Pei-Chi Shek,
& Evelyn Xiu-Ling Loo
, 2020 , Journal of Developmental Origins of Health and Disease , 11 (6) , 545--556
DOI: 10.1017/S2040174420000549
Type: article