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Research project

Long-lived Nuclear Hyperpolarization of Methyl Groups

Project overview

This project consists of the hyperpolarization of long-lived states in methyl groups and their isotopomers. The project makes use of solution NMR and dissolution-DNP equipment.

Staff

Lead researcher

Professor Malcolm Levitt

Professor of Chemistry

Research interests

  • Magnetic Resonance
  • Endofullerenes
Other researchers

Professor Richard Brown

Professor of Organic Chemistry

Collaborating research institutes, centres and groups

Magnetic Resonance

Our main focus is finding ways to extend the timescale over which magnetic resonance can be made.

Organic Chemistry, Synthesis, Catalysis

We develop environmentally sustainable approaches to chemical manufacture that minimise chemical waste, improve product velocity and reduce the need to isolate intermediates.

Research outputs

Symmetry constraints on spin dynamics: application to hyperpolarized NMR
Malcolm H. Levitt
, 2015 , Journal of Magnetic Resonance , 1--9
DOI: 10.1016/j.jmr.2015.08.021
Type: article
Long-lived nuclear spin states far from magnetic equivalence
Gabriele Stevanato,
Soumya Singha Roy,
Joe Hill-Cousins,
Ilya Kuprov,
Lynda Jane Brown,
Richard Brown,
Giuseppe Pileio,
& Malcolm H. Levitt
, 2015 , Physical Chemistry Chemical Physics , 1--11
DOI: 10.1039/C4CP05704J
Type: article
Enhancement of quantum rotor NMR signals by frequency-selective pulses
Soumya Singha Roy,
Jean-Nicolas Dumez,
Gabriele Stevanato,
Benno Meier,
Joseph T. Hill-Cousins,
Richard C.D. Brown,
Giuseppe Pileio,
& Malcolm H. Levitt
, 2015 , Journal of Magnetic Resonance , 250 , 25--28
DOI: 10.1016/j.jmr.2014.11.004
Type: article
NMR of 133Cs+ in stretched hydrogels: one-dimensional, z- and NOESY spectra, and probing the ion’s environment in erythrocytes
Philip W. Kuchel,
Dmitry Shishmarev,
Max Puckeridge,
Malcolm Levitt,
Christoph Naumann,
& Bogdan E. Chapman
, 2015 , Journal of Magnetic Resonance , 261 , 110--120
DOI: 10.1016/j.jmr.2015.10.011
Type: article
Letter. Synthesis of an isotopically labeled naphthalene derivative that supports a long-lived nuclear singlet state
Joseph Hill-Cousins,
Ionut-Alexandru Pop,
Giuseppe Pileio,
Gabriele Stevanato,
Par Hakansson,
Soumya Singha Roy,
Malcolm Levitt,
Lynda Brown,
& Richard Brown
, 2015 , Organic Letters , 17 (9) , 2150--2153
DOI: 10.1021/acs.orglett.5b00744
Type: article