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Research project

PRINCESS trial

Research groups:
Lead researcher:

Professor Philip Calder
Other researchers:

Professor Paul Little,

Emeritus Professor Michael Moore
Research funder:

National Institute of Health and Care Research
Status:

Not active

Project overview

This study is now complete, please see associated publications. The PRINCESS trial will assess the efficacy and mechanisms of a nutritional intervention (daily probiotics) to enhance immune function and reduce infection in care home residents. This is anticipated to reduce antibiotic prescribing for common infectious diseases in a high-risk population.

Staff

Lead researcher

Professor Philip Calder

Professor Philip Calder

Head of School

Connect with Philip

Email: p.c.calder@soton.ac.uk

Other researchers

PL

Professor Paul Little

Professor in Primary Care Research

Connect with Paul

Email: p.little@soton.ac.uk

Emeritus Professor Michael Moore

Emeritus Professor Michael Moore

Connect with Michael

Email: mvm198@soton.ac.uk

Collaborating research institutes, centres and groups

Primary Care Research Centre

We increase understanding of the psychosocial effects of cancer on daily life to improve health outcomes and help people live well.

Research outputs

Effect of probiotic use on antibiotic administration among care home residents: a randomized clinical trial

Christopher C. Butler Butler,

Mandy Lau,

David Gillespie,

Eleri Owen-Jones,

Mark Lown,

Mandy Wootton,

Philip Calder,

Antony J. Bayer,

Michael Moore,

Paul Little,

Jane Davies,

Alison Edwards,

Victoria Shepherd,

Kerenza Hood,

F. D. Richard Hobbs,

Mina Davoudianfar,

Heather Rutter,

Helen Stanton,

Rachel Lowe,

Richard Fuller,

& Nick Francis

, 2020 , JAMA , 324 (1) , 47--56

DOI: 10.1001/jama.2020.8556

Type: article

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