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Research project


Project overview

This study is now complete, please see associated publications. The PRINCESS trial will assess the efficacy and mechanisms of a nutritional intervention (daily probiotics) to enhance immune function and reduce infection in care home residents. This is anticipated to reduce antibiotic prescribing for common infectious diseases in a high-risk population.


Lead researcher

Professor Philip Calder

Head of School

Connect with Philip

Other researchers

Professor Paul Little

Professor in Primary Care Research

Connect with Paul

Research outputs

Christopher C. Butler Butler,
Mandy Lau,
David Gillespie,
Eleri Owen-Jones,
Mandy Wootton,
Antony J. Bayer,
Paul Little,
Jane Davies,
Alison Edwards,
Victoria Shepherd,
Kerenza Hood,
F. D. Richard Hobbs,
Mina Davoudianfar,
Heather Rutter,
Helen Stanton,
Rachel Lowe,
Richard Fuller,
, 2020 , JAMA , 324 (1) , 47--56
Type: article
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