This study is now complete, please see associated publications. The PRINCESS trial will assess the efficacy and mechanisms of a nutritional intervention (daily probiotics) to enhance immune function and reduce infection in care home residents. This is anticipated to reduce antibiotic prescribing for common infectious diseases in a high-risk population.
Effect of probiotic use on antibiotic administration among care home residents: a randomized clinical trial
Christopher C. Butler Butler,
Antony J. Bayer,
F. D. Richard Hobbs,
Richard Fuller,, 2020 , JAMA , 324 (1) , 47--56