Paul Stephen Little

Research

Research projects

Active projects

Strategies to reduce the burden of antibiotic resistance in China

Researchers:

Professor Paul Little

Sponsor: Medical Research Council

CLASP Cancer: Life Affirming Survivorship support in Primary care

Researchers:

Professor Paul Little

Professor Lucy Yardley ,

Professor Geraldine Leydon ,

Professor Dankmar Böhning ,

Professor Michael Moore ,

Professor Claire Foster ,

Doctor Adam Geraghty ,

Professor Alison Richardson ,

Professor Gareth Griffiths

Sponsor: National Institute of Health and Care Research

SPCR Tranche IV Capacity Award

Researchers:

Professor Paul Little

Professor Hazel Everitt ,

Doctor Emma Teasdale ,

Doctor Merlin Willcox

Sponsor: National Institute of Health and Care Research

RECON programme

Researchers:

Professor Paul Little

Professor Lucy Yardley ,

Professor Tony Kendrick ,

Professor Gareth Griffiths

Sponsor: National Institute of Health and Care Research

STREAM programme

Researchers:

Professor Paul Little

Professor Gareth Griffiths

Sponsor: National Institute of Health and Care Research

RECUR programme

Researchers:

Professor Paul Little

Professor Lucy Yardley ,

Doctor Adam Geraghty ,

Professor Gareth Griffiths ,

Professor Michael Moore ,

Doctor Ben Ainsworth

Sponsor: National Institute of Health and Care Research

STOP AMR - decision aids

Researchers:

Professor Paul Little

Doctor Mark Lown

Sponsor: National Institute of Health and Care Research

PANORAMIC - Platform Adaptive trial of NOvel antivRals for eArly treatMent of COVID-19 In the Community

Researchers:

Professor Paul Little

Doctor Mark Lown

Sponsor: National Institute of Health and Care Research

Stop-AMR -development

Researchers:

Professor Paul Little

Professor Sue Latter

Sponsor: National Institute of Health and Care Research

AIM study

Researchers:

Doctor Hajira Dambha-Miller

Doctor Glenn Simpson ,

Professor Paul Little ,

Professor Michael Boniface

Developing a patient-centred evidence-based intervention to address distress in the context of chronic MSK pain

Researchers:

Doctor Adam Geraghty

Professor Paul Little ,

Professor Michael Moore

Sponsor: Versus Arthritis

Acne Care Online

Researchers:

Professor Miriam Santer

Doctor Ingrid Muller ,

Professor Paul Little ,

Professor Nick Francis ,

Professor Lucy Yardley ,

Professor Gareth Griffiths ,

Doctor Rosie Essery ,

Doctor Mary Steele ,

Miss Charlotte Cairns

The PREFIX study

Researchers:

Professor Nick Francis

Professor Tristan Clark ,

Professor Paul Little ,

Doctor Ingrid Muller ,

Doctor Nazrul Islam ,

Doctor Taeko Becque

Cellulitis optimal antibiotic treatment (COAT) study

Researchers:

Professor Nick Francis

Professor Paul Little ,

Doctor Andrew Cook ,

Professor Miriam Santer ,

Professor Robert Read

Sponsor: National Institute of Health and Care Research

DEFINE: Development and evaluation of a FeNO-guided asthma management intervention in primary care

Researchers:

Professor Paul Little

Sponsor: National Institute of Health and Care Research

Mandy Fader: Development of a mixed (reusable/disposable) catheter management pakcage for users of intermittent catheterisation

Researchers:

Professor Mandy Fader

Doctor Jacqui Prieto ,

Doctor Sandra Wilks ,

Professor Michael Moore ,

Doctor Jeremy Jones ,

Professor Charles Keevil ,

Professor Paul Little ,

Professor Issy Reading

Sponsor: National Institute for Health Research Academy

REDUCE study

Researchers:

Professor Tony Kendrick

Doctor Judith Joseph ,

Professor Geraldine Leydon ,

Professor Paul Little ,

Professor Michael Moore ,

Doctor Adam Geraghty ,

Professor Gareth Griffiths

Sponsor: National Institute of Health and Care Research

SAFA study (Spironolactone for Adult Female Acne)

Researchers:

Professor Miriam Santer

Professor Paul Little ,

Doctor Ingrid Muller ,

Professor Gareth Griffiths ,

Professor Nick Francis

Sponsor: National Institute of Health and Care Research

MACRO Defining best management for adults with chronic rhinosinusitis

Researchers:

Professor Paul Little

Sponsor: National Institute of Health and Care Research

Microbiology IPD

Researchers:

Professor Nick Francis

Professor Paul Little

Sponsor: National Institute of Health and Care Research

PROMPPT Management of Opioids and Persistent Pain (MOPP) Study

Researchers:

Professor Miriam Santer

Professor Paul Little

Sponsor: National Institute of Health and Care Research

Treat to Target (T2) in Gout Trial

Researchers:

Professor Miriam Santer

Professor Paul Little

Sponsor: National Institute of Health and Care Research

Acne Care Online

Researchers:

Professor Miriam Santer

Professor Paul Little ,

Professor Lucy Yardley ,

Doctor Ingrid Muller ,

Doctor Taeko Becque ,

Professor Gareth Griffiths ,

Professor Nick Francis

Sponsor: National Institute of Health and Care Research

The development and evaluation of population clusters for integrated health and social care: A mixed method study on multimorbidity in England (AIM study)

Researchers:

Doctor Hajira Dambha-Miller

Professor Paul Little ,

Professor Hazel Everitt ,

Professor Michael Boniface ,

Professor Miriam Santer

Sponsor: National Institute of Health and Care Research

Engaging adolescents in changing behaviour (EACh-B): a programme of research to improve the diets and physical activity levels of teenagers

Researchers:

Professor Mary Barker

Professor Paul Little ,

Professor Cyrus Cooper ,

Doctor Kath Woods-Townsend ,

Professor Joanne Lord ,

Doctor Leanne Morrison ,

Professor Keith Godfrey ,

Professor Marcus Grace ,

Emeritus Professor Hazel Inskip ,

Professor Janis Baird

Sponsor: National Institute of Health and Care Research

Talking in Primary Care 2 (TIP2)

Researchers:

Professor Hazel Everitt

Professor Paul Little ,

Doctor Don Cruickshank ,

Professor Flis Bishop ,

Professor Geraldine Leydon ,

Doctor Leanne Morrison ,

Doctor Jane Vennik

Sponsor: National Institute of Health and Care Research

Completed projects

R-GNOSIS - EU FP7- P Little

Researchers:

Professor Paul Little

Professor Michael Moore

Sponsor: European Union

The Bactoblis® study: a feasibility study assessing compliance, acceptability and colonisation with different dosing regimens of the probiotic supplement Streptococcus salivarius K12 (Bactoblis®) in adults

Researchers:

Professor Paul Little

P Little NIHR ASPEN feasibility study

Researchers:

Professor Paul Little

Professor Lucy Yardley ,

Professor Lisa Roberts ,

Professor Maria Stokes

Sponsor: National Institute of Health and Care Research

NSPCR Local Administration 1

Researchers:

Professor Paul Little

Sponsor: National Institute of Health and Care Research

CEDAR - Children's drops for ear pain in acute otitis media

Researchers:

Professor Paul Little

Sponsor: National Institute of Health and Care Research

Little NIHR Self measurement and management using the internet for lowering blood pressure in everyday practice

Researchers:

Professor Paul Little

Professor Lucy Yardley

Sponsor: National Institute of Health and Care Research

Prof P. Little: SPCR Administrative Funds

Researchers:

Professor Paul Little

Professor Hazel Everitt ,

Professor Miriam Santer ,

Professor Geraldine Leydon ,

Professor Michael Moore ,

Professor Tony Kendrick

Sponsor: National Institute of Health and Care Research

P Little FATIGUE NIHR SPCR

Researchers:

Professor Paul Little

Professor Michael Moore ,

Professor Geraldine Leydon ,

Professor Tony Kendrick

Sponsor: National Institute of Health and Care Research

Prof P. Little: Protocol for scoping study on the effectiveness and cost effectiveness of CAM/IM treatments for patients with multimobidity comprising pain and mental health problems in priamry care in the UK

Researchers:

Professor Paul Little

Sponsor: National Institute of Health and Care Research

SPCR: Prof P. Little: CANDID (extension)

Researchers:

Professor Paul Little

Sponsor: National Institute of Health and Care Research

Prof P. Little: The National School for Primary Care Research - Capacity Building Award

Researchers:

Professor Paul Little

Sponsor: National Institute of Health and Care Research

Prof P. Little: Addressing the translation gap for complex interventions in primary care

Researchers:

Professor Paul Little

Professor Hazel Everitt

Sponsor: National Institute of Health and Care Research

Prof Little: Capacity Building Award

Researchers:

Professor Paul Little

Sponsor: National Institute of Health and Care Research

ARTIC PC

Researchers:

Professor Paul Little

Sponsor: National Institute of Health and Care Research

Pre-GRACE

Researchers:

Professor Paul Little

Sponsor: National Institute of Health and Care Research

Prof P. Little: Montelukast in the treatment of acute persistant cough

Researchers:

Professor Paul Little

Professor Michael Moore

Sponsor: National Institute of Health and Care Research

CANDID - Cancer Diagnosis Decision Rules

Researchers:

Professor Paul Little

Professor Geraldine Leydon

Sponsor: National Institute of Health and Care Research

Prof P. Little: Fatigue: acute fatigue Assessment and Management in Everyday practice (FAME)

Researchers:

Professor Paul Little

Sponsor: National Institute of Health and Care Research

P Little University of Birmingham NSPCR Capacity Building Award

Researchers:

Professor Paul Little

Professor Lucy Yardley

Sponsor: National Institute of Health and Care Research

P Little TARGET

Researchers:

Professor Paul Little

Sponsor: National Institute of Health and Care Research

Little - Solent NHS RCF - Joseph Little

Researchers:

Professor Paul Little

Sponsor: National Institute of Health and Care Research

P Little Primary care Infection Management for Everyday practice PRIME

Researchers:

Professor Paul Little

Professor Geraldine Leydon ,

Professor Lucy Yardley ,

Professor Michael Moore ,

Doctor Gary Wills

Sponsor: National Institute of Health and Care Research

Prof P. Little: Benefits of Aldosterone Receptor Antagonism in Chronic Kidney Disease (BARACK D) Trial

Researchers:

Professor Paul Little

Sponsor: National Institute of Health and Care Research

POWER

Researchers:

Professor Paul Little

Professor Chris Byrne ,

Doctor Mark Weal ,

Professor Lucy Yardley ,

Professor Michael Moore ,

Emeritus Professor Barrie Margetts ,

Professor Peter Smith

Sponsor: National Institute of Health and Care Research

Prof P. Little: Treating acute gout in primary care

Researchers:

Professor Paul Little

Sponsor: National Institute of Health and Care Research

SPCR: COVID Bridging Funding

Researchers:

Professor Paul Little

Sponsor: National Institute of Health and Care Research

Prof P. Little: Capacity Building Award (Seedcorn)

Researchers:

Professor Paul Little

Sponsor: National Institute of Health and Care Research

Little - NIHR (Bristol) Preparing for Improving the use of NHS Primary Care Services and Antibiotics for Children with Respiratory Tract Infections (PREINACT)

Researchers:

Professor Paul Little

Professor Lucy Yardley

Sponsor: National Institute of Health and Care Research

Little - NIHR SPCR (via Manchester) - Investigating Burnout in general practitioners and indicators of suboptimal patient care using the Clinical Practice Research Datalink (Nov 17)

Researchers:

Professor Paul Little

Sponsor: National Institute of Health and Care Research

SNIFSII Saline Nasal Irrigation for Acute Sinusitis

Researchers:

Professor Paul Little

Professor Michael Moore ,

Doctor Ben Ainsworth

Sponsor: National Institute of Health and Care Research

Little - NIHR/UCL - CAP IT

Researchers:

Professor Paul Little

Professor Saul Faust

Sponsor: National Institute of Health and Care Research

P Little SUHT Pragmatic Obesity Web management for Efficient Routine practice POWER

Researchers:

Professor Paul Little

Professor Lucy Yardley ,

Professor Michael Moore

Sponsor: National Institute of Health and Care Research

Prof P. Little: Oral steriods in acute cough

Researchers:

Professor Paul Little

Professor Michael Moore

Sponsor: National Institute of Health and Care Research

Little - SPCR - Quantifying changes and appropriateness of UK primary care clinical activity and workload: A 15-year retrospective analysis of diagnostic test use

Researchers:

Professor Paul Little

Sponsor: National Institute of Health and Care Research

Diabetes Literacy-EU FP7-Lucy Yardley

Researchers:

Professor Lucy Yardley

Professor Paul Little

Sponsor: European Union

Yardley Dunhill Medical Trust Online Dizziness Intervention for older adults

Researchers:

Professor Lucy Yardley

Doctor Adam Geraghty ,

Professor Paul Little ,

Doctor Sarah Kirby

Sponsor: The Dunhill Medical Trust

Prof Lucy Yardley Wellcome Trust KCL cluster randomised trials

Researchers:

Professor Lucy Yardley

Professor Paul Little

Sponsor: Wellcome Trust

Lucy Brindle: Identifying optimal communication about direct access tests and referral for cancer investigation

Researchers:

Doctor Lucy Brindle

Professor Geraldine Leydon ,

Professor Paul Little ,

Emeritus Professor Anne Rogers

Sponsor: Cancer Research UK

Dr M. Moore: Do oral corticosteroids provide clinical and cost-effective symptom relief for sore throat (TOAST)

Researchers:

Professor Michael Moore

Professor Paul Little

Sponsor: National Institute of Health and Care Research

Dr G. Leydon - Understanding the delayed prescibing of antibiotics for respiratory tract infection inprimary care

Researchers:

Professor Geraldine Leydon

Professor Michael Moore ,

Professor Paul Little

Sponsor: National Institute of Health and Care Research

Safety of reducing antibiotic prescribing in primary care. New evidence from electronic health records

Researchers:

Professor Michael Moore

Professor Paul Little

Sponsor: National Institute of Health and Care Research

Yardley, NIHR, DIPSS

Researchers:

Professor Lucy Yardley

Professor Paul Little ,

Doctor Adam Geraghty ,

Professor Peter Smith ,

Doctor Mark Weal

Sponsor: National Institute for Health Research

Yardley NIHR HTA E-coachER Project

Researchers:

Professor Lucy Yardley

Professor Paul Little

Sponsor: National Institute of Health and Care Research

Prof M. Moore: The early use of Antibiotics in at Rish Children with InfluEnza (ARCHIE)

Researchers:

Professor Michael Moore

Professor Paul Little

Sponsor: National Institute of Health and Care Research

Longitudinal study of suspected COVID-19 in the community (RTO-Covid)

Researchers:

Professor Nick Francis

Professor Paul Little ,

Professor Lucy Yardley ,

Doctor Adam Geraghty ,

Professor Michael Moore

Sponsor: National Institute of Health and Care Research

Williamson HTA AIR Study Autoinflation in school age children with OME in primary care

Researchers:

Professor Paul Little

Sponsor: National Institute of Health and Care Research

Dr A. Geraghty: INDRA-Project

Researchers:

Doctor Adam Geraghty

Professor Lucy Yardley ,

Professor Michael Moore ,

Professor Paul Little

Sponsor: National Institute of Health and Care Research

PRINCESS trial

Researchers:

Professor Philip Calder

Professor Paul Little ,

Professor Michael Moore

Sponsor: National Institute of Health and Care Research

Dr A. Geraghty: Distinguishing emotional distress from emotional disorder in prmary care

Researchers:

Doctor Adam Geraghty

Professor Michael Moore ,

Professor Paul Little

Sponsor: National Institute of Health and Care Research

Moore - SPCR - A retrospective cohort study in the HHR of the primary care antecedent of admission with sepsis (October 2016)

Researchers:

Professor Michael Moore

Professor Paul Little

Sponsor: National Institute of Health and Care Research

Developing an inclusive approach to multidimensional measurement of mental health symptoms in people in UK primary care

Researchers:

Doctor Adam Geraghty

Professor Paul Little ,

Professor Tony Kendrick ,

Professor Miriam Santer ,

Professor Michael Moore

Sponsor: National Institute of Health and Care Research

EMPATHICA - Expectation Management for Patients in Primary Care: Developing and Feasibility Testing a New Digital Intervention for Practitioners

Researchers:

Professor Hazel Everitt

Professor Lucy Yardley ,

Professor Paul Little ,

Doctor Leanne Morrison ,

Professor Flis Bishop

Sponsor: National Institute of Health and Care Research

Supporting Parents and Carers of children with eczema (SPaCE web based intervention feasibility trial)

Researchers:

Professor Miriam Santer

Professor Lucy Yardley ,

Professor Paul Little

Sponsor: National Institute of Health and Care Research

Prof Lucy Yardley NIHR-RfPB

Researchers:

Professor Lucy Yardley

Professor Paul Little

Sponsor: National Institute of Health and Care Research

Patterns of remission in type 2 diabetes

Researchers:

Doctor Hajira Dambha-Miller

Professor Paul Little ,

Professor Hazel Everitt

Sponsor: National Institute of Health and Care Research

Integrating health and social care: A mixed methods study in primary care

Researchers:

Doctor Hajira Dambha-Miller

Professor Paul Little ,

Professor Hazel Everitt ,

Professor Miriam Santer ,

Doctor Simon Fraser

Sponsor: National Institute of Health and Care Research

Moore - NIHR HTA 16/85/01 - Immediate oral, immediate topical or delayed oral antibiotics for acute otitis media with discharge (the Runny Ear STudy - REST)

Researchers:

Professor Michael Moore

Professor Paul Little

Sponsor: National Institute of Health and Care Research

Dr M. Moore: Patient safety in Primary care

Researchers:

Professor Michael Moore

Professor Paul Little

Sponsor: National Institute of Health and Care Research

Yardley - NIHR HTA PIMMS

Researchers:

Professor Lucy Yardley

Professor Paul Little

Sponsor: National Institute of Health and Care Research

Bath Additives in the Treatment of childhood Eczema: BATHE Study

Researchers:

Professor Miriam Santer

Ms Maria (Mary) Chorozoglou ,

Professor Paul Little

Sponsor: National Institute of Health and Care Research

NIHR RfBP - Delayed antibiotic prescribing for respiratory tract infections - an evidence synthesis of individual patient date (August 2016)

Researchers:

Professor Dankmar Böhning ,

Professor Paul Little ,

Professor Michael Moore

Sponsor: National Institute of Health and Care Research

Dr A. Geraghty: Internet Intervention Supporting Management of Low Back Pain in Primary Care (Support Back) PB-PG-1111-26080

Researchers:

Doctor Adam Geraghty

Professor Lucy Yardley ,

Professor Lisa Roberts ,

Professor Paul Little

Sponsor: National Institute of Health and Care Research

Lown - SPCR - Prolonged Antibiotic Use, Inflammation and Obesity (PRBITY)

Researchers:

Doctor Mark Lown

Professor Paul Little ,

Professor Michael Moore

Sponsor: National Institute of Health and Care Research

OPTIMISE - Optimising Treatment for Mild Systolic hypertension in the Elderly

Researchers:

Doctor Mark Lown

Professor Paul Little

Sponsor: National Institute of Health and Care Research

Dr M. Moore: ATAFUTI

Researchers:

Professor Michael Moore

Professor Geraldine Leydon ,

Professor Paul Little ,

Mrs Louise Stanton

Sponsor: National Institute of Health and Care Research

4S Sore Throat Study (Scores and Swabs to Self-assess Sore Throats)

Researchers:

Professor Nick Francis

Professor Paul Little ,

Doctor Ingrid Muller ,

Doctor Mark Lown ,

Professor Michael Moore

Sponsor: National Institute of Health and Care Research

ACTIB - Accessing Cognitive Therapy in Irritable Bowel

Researchers:

Professor Hazel Everitt

Professor Paul Little ,

Professor Flis Bishop

Sponsor: National Institute of Health and Care Research

Dr G. Leydon: Eliciting Patient Concerns (EPaC)

Researchers:

Professor Geraldine Leydon

Professor Paul Little ,

Professor Michael Moore

Sponsor: National Institute of Health and Care Research

ECO Eczema Care Online

Researchers:

Professor Miriam Santer

Professor Paul Little ,

Professor Lucy Yardley ,

Doctor Ingrid Muller ,

Professor Gareth Griffiths

Sponsor: National Institute of Health and Care Research

act EPs7630 (Kaloba) for lower respiratory tract infection in adults

Researchers:

Professor Michael Moore

Professor Paul Little ,

Professor Gareth Griffiths

Sponsor: National Institute of Health and Care Research

SPCR: Dr G. Leydon: UNderstanding medIcal and no-medical anTibiotic prescribing for rEspiratory tract infections in primary care out of hours services: a qualitative analysis

Researchers:

Professor Geraldine Leydon

Professor Michael Moore ,

Professor Paul Little

Sponsor: National Institute of Health and Care Research

SupportBack2

Researchers:

Doctor Adam Geraghty

Professor Lisa Roberts ,

Professor Paul Little ,

Professor Lucy Yardley ,

Professor Gareth Griffiths

Sponsor: National Institute of Health and Care Research

OPEN: Out of Hours Prescribing: Enhancing Communication

Researchers:

Professor Geraldine Leydon

Professor Paul Little ,

Professor Michael Moore

Sponsor: National Institute of Health and Care Research

SPCR: Prof M. Moore: ATAFUTI (extension)

Researchers:

Professor Michael Moore

Professor Paul Little ,

Professor Geraldine Leydon

Sponsor: National Institute of Health and Care Research

Moore - SPCR - Microbiology of throat swabs collected when patients present to primary care with acute cough

Researchers:

Professor Michael Moore

Professor Paul Little

Sponsor: National Institute of Health and Care Research

Mandy Fader: Antibiotic treatment for intermittent bladder catherterisation: A randomised controlled trial of once daily prophylaxis (AnTIC)

Researchers:

Professor Mandy Fader

Professor Paul Little

Sponsor: National Institute of Health and Care Research

ACE-Inhibitors/Angiotensin Receptor Blockers and risk of death for people infected with COVID-19: a prospective cohort study

Researchers:

Doctor Hajira Dambha-Miller

Professor Paul Little

Sponsor: National Institute of Health and Care Research

Professor Paul Little

Connect with Paul

Research

Research projects

Active projects

Completed projects

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