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Dr Negusse T. Kitaba BSc, MSc, PhD

Research Fellow in Bioinformatics/Epigenetics

Dr Negusse T. Kitaba's photo

Research Fellow in Bioinformatics/Epigenetics within the Faculty of Medicine at the University of Southampton.

Dr Negusse graduated from Addis Ababa University with a BSc in Biological Science and an MSc in Biodiversity.  He completed his MSc in Bioinformatics at Cardiff University.  He undertook research into gene regulation, pathway analysis and protein structure prediction to support drug discovery at the University of South Wales, graduating with a PhD in Computational Biology in 2015.

Dr Negusse has a keen interest in understanding how genetics and environmental interactions affect gene function and disease outcomes.  He joined the University of Southampton, Faculty of Biological Science in 2017 where he investigated the effect of maternal gestational diabetes on the offspring epigenome.  His current work in the Faculty of Medicine involves studying the transgenerational effect of paternal smoking. 


Appointments held

Research interests

My current research mainly involves working with DNA methylation data to identify epigenetic marks for periconceptional paternal smoking exposure across generations. This Epigenome Wide Association Study is part of the Rhinessa multicentre population project. 

My expertise includes integrating multi-omic data such as SNP, transcriptome, methylation and interactome (PPI) at the system level to understand the molecular mechanisms underlying the origins of complex diseases. 

In my former position, I worked on the epigenetic effects of Maternal Gestation Diabetes (GDM) using the UPBEAT Offspring data supported by Diabetes UK.

Research group

Human Development and Health

Affiliate research group

Rhinessa Offspring Cohort Study

Member of the International Society for Computational Biology (2011 to present) 

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Dr Negusse T. Kitaba
Duthie Building, Room DA009, Level, A
Human Genetics and Genomic Medicine
Human Development and Health Academic Unit
Faculty of Medicine
Southampton General Hospital
Tremona Road
Southampton, SO16 6YD

Tel: +44 (0) 2381 208 783

Room Number : SGH/DA009/MP887

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