Interdisciplinary Dementia and Ageing Centre

Publications

Browse our published work and read our findings.

ApoE4 astrocytes secrete basement membranes rich in fibronectin and poor in laminin compared to ApoE3 astrocytes

Abby Keable,

Ronan O'Neill,

Matthew MacGregor Sharp,

Maureen Gatherer,

Ho Ming Yuen,

David Annandale Johnston,

Roy Oliver Weller,

& Roxana Octavia Carare

, 2020 , International Journal of Molecular Sciences , 21 (12) , 1--13

DOI: 10.3390/ijms21124371

Type: article

Neurofilaments: neurobiological foundations for biomarker applications

Arie R. Gafson,

Nicolas R. Barthélemy,

Pascale Bomont,

Roxana-Octavia Carare,

Heather D. Durham,

Jean-Pierre Julien,

Jens Kuhle,

David Leppert,

Ralph A. Nixon,

Roy O. Weller,

Henrik Zetterberg,

& Paul M. Matthews

, 2020 , Brain , 143 (7) , 1975–1998

DOI: 10.1093/brain/awaa098

Type: article

UK consensus on pre-clinical vascular cognitive impairment functional outcomes assessment

Aisling McFall,

Tuuli M Hietamies,

Ashton Bernard,

Margaux Aimable,

Stuart M Allan,

Philip M Bath,

Gaia Brezzo,

Roxana O Carare,

Hilary V Carswell,

Andrew N Clarkson,

Gillian Currie,

Tracy D Farr,

Jill H Fowler,

Mark Good,

Atticus H Hainsworth,

Catherine Hall,

Karen Horsburgh,

Rajesh Kalaria,

Patrick Kehoe,

Catherine Lawrence,

Malcolm Macleod,

Barry W McColl,

Alison McNeilly,

Alyson A Miller,

Scott Miners,

Vincent Mok,

Michael O'Sullivan,

Bettina Platt,

Emily S Sena,

Matthew Sharp,

Patrick Strangward,

Stefan Szymkowiak,

Rhian M Touyz,

Rebecca C Trueman,

Claire White,

Chris McCabe,

Lorraine M Work,

& Terence J Quinn

, 2020 , Journal of Cerebral Blood Flow & Metabolism , 40 (7) , 1402--1414

DOI: 10.1177/0271678X20910552

Type: article

Vasomotion drives periarterial drainage of Aβ from the brain

Roxana-Octavia Carare,

Roxana Aldea,

Diederik Bulters,

Aiman Alzetani,

Anthony Birch,

Giles Richardson,

& Roy O. Weller

, 2020 , Neuron , 105 (3) , 400--401

DOI: 10.1016/j.neuron.2020.01.011

Type: article

The pattern of AQP4 expression in the ageing human brain and in cerebral amyloid angiopathy

Raisah Owasil,

Ronan O'Neill,

Abby Keable,

Jacqui Nimmo,

Matthew MacGregor Sharp,

Louise Kelly,

Satoshi Saito,

Julie E Simpson,

Roy O Weller,

Colin Smith,

Johannes Attems,

Stephen B Wharton,

Ho Ming Yuen,

& Roxana O Carare

, 2020 , International Journal of Molecular Sciences , 21 (4)

DOI: 10.3390/ijms21041225

Type: article

Demonstrating a reduced capacity for removal of fluid from cerebral white matter and hypoxia in areas of white matter hyperintensity associated with age and dementia

Matthew MacGregor Sharp,

Satoshi Saito,

Abby Keable,

Maureen Gatherer,

Roxana Aldea,

Nivedita Agarwal,

Julie E. Simpson,

Stephen B. Wharton,

Roy O. Weller,

& Roxana O. Carare

, 2020 , Acta Neuropathologica Communications , 8 (1)

DOI: 10.1186/s40478-020-01009-1

Type: article

Solving an old dogma

Matthew MacGregor Sharp,

Theodore P Criswell,

Howard Dobson,

Ciara Finucane,

Ajay Verma,

& Roxana O Carare

, 2019 , Frontiers in Aging Neuroscience , 11

DOI: 10.3389/fnagi.2019.00289

Type: article

Porphyromonas gingivalis infection induces Amyloid-β accumulation in monocytes/macrophages

Ran Nie,

Zhou Wu,

Junjun Ni,

Fan Zeng,

Weixian Yu,

Yufeng Zhang,

Tomoko Kadowaki,

Haruhiko Kashiwazaki,

Jessica L. Teeling,

Yanmin Zhou,

& Sim Singhrao

, 2019 , Journal of Alzheimer's Disease , 72 (2) , 479--494

DOI: 10.3233/JAD-190298

Type: article

An evaluation of Drosophila as a model system for studying tauopathies such as Alzheimer's disease

Lovesha Sivanantharajah,

Amritpal Mudher,

& David Shepherd

, 2019 , Journal of Neuroscience Methods , 319 , 77--88

DOI: 10.1016/j.jneumeth.2019.01.001

Type: article

Refusal and resistance to care by people living with dementia being cared for within acute hospital wards: an ethnographic study

Katie Featherstone,

Andy Northcott,

Jane Harden,

Karen Harrison Dening,

Rosie Tope,

Sue Bale,

& Jacqueline Bridges

, 2019 , Health Services and Delivery Research , 7 (11) , 1--92

DOI: 10.3310/hsdr07110

Type: article