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Research project

Boche - ARUK - 3D imaging for Life Sciences - (April 18)

Staff

Lead researcher

Professor Delphine Boche

Professor of Neuroimmunopathology

Research interests

  • Delphine serves on a range of neuroscience research projects focusing on neuroinflammation and neurodegeneration.
  • Her main research interest is to develop a greater understanding of the role of neuroinflammation in relation with ageing, neurological diseases and systemic inflammation, using the approaches of human brain analysis. Her research focuses on microglia, the immune cells of the brain, where she has developed protocols to immunophenotype microglia in humans using markers relating to a specific function allowing us to investigate the role of these cells in different neurological conditions.

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Other researchers

Professor Roxi Carare

Head of School

Research interests

  • Causes and new therapeutic strategies for dementias and other neurodegenerative diseases
  • New early diagnostic measures in dementia based on biomarkers from the nose

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Professor James Nicoll

Professor of Neuropathology

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Doctor Felino Cagampang PhD

Associate Professor

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Doctor Sandrine Willaime-Morawek

Associate Professor

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Doctor Arjuna Ratnayaka

Associate Professor

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Collaborating research institutes, centres and groups

Clinical Neurosciences

Examining how clinical and environmental factors can affect brain development.

Research outputs

A 3D-induced pluripotent stem cell-derived human neural culture model to study certain molecular and biochemical aspects of Alzheimer’s disease
Preeti Prasannan,
Elodie Jane Siney,
Shreyasi Chatterjee,
David Johnston,
Mohammad Shah,
Amritpal Mudher,
& Sandrine Willaime-Morawek
, 2022 , In Vitro Models , 1 , pages447–462
DOI: 10.1007/s44164-022-00038-5
Type: article
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