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Research project

J Holloway: Trangenerational Epigenetic inheritance of allergy in a Multigenerational Cohort

Staff

Lead researchers

Professor John Holloway PhD, FHEA, FERS

Associate VP Interdisciplinary Research
Research interests
  • Human genetics
  • Epigenetics
  • Respiratory Disease
Connect with John

Email: J.W.Holloway@soton.ac.uk

Research outputs

Filaggrin mutations increase allergic airway disease in childhood and adolescence through interactions with eczema and aeroallergen sensitization
Adrian Chan, William Terry, Hongmei Zhang, Wilfried Karmaus, Susan Ewart, John W Holloway, Graham Roberts, Ramesh Kurukulaaratchy & Syed Hasan Arshad, 2018, Clinical & Experimental Allergy, 48(2), 147-155
DOI: 10.1111/cea.13077
Type: article
Expression of the filaggrin gene in umbilical cord blood predicts eczema risk in infancy
Ali H Ziyab, Susan Ewart, Gabrielle A Lockett, Hongmei Zhang, Syed Arshad, John W Holloway & Wilfried Karmaus, 2017, Clinical & Experimental Allergy, 47(9), 1185-1192
DOI: 10.1111/cea.12956
Type: article
The role of DNA methylation in type 2 diabetes aetiology – using genotype as a causal anchor
Hannah Elliot, Hashem Shihab, Gabrielle A. Lockett, John Holloway, Allan F. McRae, George Davey-Smith, Susan M. Ring, Tom R. Gaunt & Caroline L. Relton, 2017, Diabetes, 66(6), 1713-1722
DOI: 10.2337/db16-0874
Type: article
Multi-generational cohorts in asthma and allergy
Hasan Arshad, Wilfried Karmaus, Hongmei Zhang & John W. Holloway, 2017, Journal of Allergy and Clinical Immunology, 139(2), 415-421
DOI: 10.1016/j.jaci.2016.12.002
Type: article
Tetanus vaccination is associated with differential DNA-methylation: Reduces the risk of asthma in adolescence
Vimala Devi Janjanam, Nandini Mukherjee, Gabrielle A. Lockett, Faisal I. Rezwan, Ramesh Kurukulaaratchy, Frances Mitchell, Hongmei Zhang, Hasan Arshad, John Holloway & Wilfried Karmaus, 2016, Vaccine, 34(51), 6493-6501
DOI: 10.1016/j.vaccine.2016.10.068
Type: article