Research project

Mackay MR/J000329/1 Identifying factors required for genomic DNA methylation

Lead researchers:

Professor Deborah Mackay
Research funder:

Medical Research Council
Status:

Not active

Staff

Lead researchers

Professor Deborah Mackay

Professor of Medical Epigenetics

Connect with Deborah

Email: D.J.G.Mackay@soton.ac.uk

Research outputs

Maternal uniparental disomy of chromosome 20: a novel imprinting disorder of growth failure

Surabhi Mulchandani, Elizabeth J. Bhoj, Minjie Luo, Nina Powell-Hamilton, Kim Jenny, Karen W. Gripp, Miriam Elbracht, Thomas Eggermann, Claire L. S. Turner, I. Karen Temple, Deborah J. G. Mackay, Holly Dubbs, David A. Stevenson, Leah Slattery, Elaine H. Zackai, Nancy B. Spinner, Ian D. Krantz & Laura K. Conlin, 2015, Genetics in Medicine, 18(4), 309-315

DOI: 10.1038/gim.2015.103

Type: article

A statistical method for single sample analysis of HumanMethylation450 array data: genome-wide methylation analysis of patients with imprinting disorders

Faisal I. Rezwan, Louise E. Docherty, Rebecca L. Poole, Gabrielle A. Lockett, S. Hasan Arshad, John W. Holloway, I. Karen Temple & Deborah J.G. Mackay, 2015, Clinical Epigenetics, 7(1), 1-11

DOI: 10.1186/s13148-015-0081-5

Type: article

Very small deletions within the NESP55 gene in pseudohypoparathyroidism type 1b

Faisal I. Rezwan, Rebecca L. Poole, Trine Prescott, Joanna M. Walker, I. Karen Temple & Deborah J.G. Mackay, 2015, European Journal of Human Genetics, 23(4), 494-499

DOI: 10.1038/ejhg.2014.133

Type: article

Multilocus methylation defects in imprinting disorders

Deborah J.G. Mackay, Thomas Eggermann, Karin Buiting, Intza Garin, Irène Netchine, Agnès Linglart & Guiomar Perez de Nanclares, 2015, BioMolecular Concepts, 6(1), 47-57

DOI: 10.1515/bmc-2014-0037

Type: article

Genome-wide DNA methylation analysis of patients with imprinting disorders identifies differentially methylated regions associated with novel candidate imprinted genes

L.E. Docherty, F.I. Rezwan, R.L. Poole, H. Jagoe, H. Lake, G.A. Lockett, H. Arshad, D.I. Wilson, J.W. Holloway, I.K. Temple & D.J.G. Mackay, 2014, Journal of Medical Genetics, 51(4), 229-238

DOI: 10.1136/jmedgenet-2013-102116

Type: article