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Research project

The role of nuclear phosphoinositides in epigenetic signalling - N Divecha - BBSRC

  • Lead researchers:
    Professor Nullin Divecha
  • Research funder:
    Biotechnology & Biological Sciences Research Council
  • Status:
    Not active

Staff

Lead researchers

Professor Nullin Divecha

Professor of Cellular Signalling
Connect with Nullin

Email: N.Divecha@soton.ac.uk

Research outputs

New insights into the role and regulation of nuclear PtdIns(4,5)P2
2025
Type: thesis
Mechanisms of SARS-CoV-2 inactivation using UVC laser radiation
George Devitt, Peter B. Johnson, Niall Hanrahan, Simon I.R. Lane, Magdalena C. Vidale, Bhavwanti Sheth, Joel D. Allen, Maria V. Humbert, Cosma M. Spalluto, Rodolphe C. Herve, Karl Staples, Jonathan J. West, Robert Forster, Nullin Divecha, Chris McCormick, Max Crispin, Nils Hempler, Graeme P.A. Malcolm & Sumeet Mahajan, 2024, ACS Photonics, 11(1), 42-52
DOI: 10.1021/acsphotonics.3c00828
Type: article
PIP4K2B is mechanoresponsive and controls heterochromatin-driven nuclear softening through UHRF1
A. Poli, F.A. Pennacchio, A. Ghisleni, M. di Gennaro, M. Lecacheur, P. Nastaly, M. Crestani, F.M. Pramotton, F. Iannelli, G. Beznusenko, A. A Mironov, V. Panzetta, S. Fusco, B. Sheth, D. Poulikakos, A. Ferrari, N. Gauthier, P.A. Netti, N. Divecha & P. Maiuri, 2023, Nature Communications, 14(1)
DOI: 10.1038/s41467-023-37064-0
Type: article
Identification and optimization of a novel series of selective PIP5K inhibitors
D.M. Andrews, S. Cartic, S. Cosulich, N. Divecha, P. Faulder, V. Flemington, O. Kern, J.G. Kettle, E. MacDonald, J. McKelvie, K.G. Pike, B. Roberts, R. Rowlinson, J.M. Agnos, M. Stockley, M.E. Swarbrick, I. Treinies & M.J. Waring, 2021, Bioorganic & Medicinal Chemistry, 54
DOI: 10.1016/j.bmc.2021.116557
Type: article
Modulating phosphoinositide profiles as a roadmap for treatment in acute myeloid leukemia
S. Ratti, C. Evangelisti, S. Mongiorgi, A. De Stefano, A. Fazio, F. Bonomini, M.Y. Follo, I. Faenza, L. Manzoli, B. Sheth, M.C. Vidalle, S.T. Kimber, N. Divecha, L. Cocco & R. Fiume, 2021, Frontiers in Oncology, 11
DOI: 10.3389/fonc.2021.678824
Type: article