About
Jay completed his higher specialist training in Paediatric Ophthalmology in Southampton and Manchester and his research training through an MRC Clinical Research Training Fellowship/PhD in Ophthalmic Molecular Genetics.
"All of our research has the overarching aim of improving the lives of children with eye disorders"
Jay’s research interests cover a range of disorders affecting vision in children including nystagmus, albinism, genetic disorders of the eye, amblyopia and paediatric cataract. His team combines expertise in genetics, bioinformatics, wet-lab modelling, eye-tracking and clinical trials.
Jay is an advisor to 5 vision charities, board member for two charities, Div A representative for the UHS hospital charity, and ambassador for one foundation. He works closely with the Royal College of Ophthalmologists (RCOphth) in a number of roles including member of the genomics working group, member of the paediatric and academic subcommittees, chair of various national masterclass training courses and has represented the college for media communications and guideline development. He is the national chair of the NIHR paediatric and neuro-ophthalmology Clinical Study Group (CSG). He is an advocate of public engagement in science and has delivered many public address lectures and open floor sessions for over 10 years.
Jay and his team are passionate about translating research findings into clinical practice and improving the care for children with visual disorders by improving diagnostics, developing new treatments and ways of working and disseminating best practice.
Research
Research groups
Research projects
Active projects
Completed projects
Researchers:
Researchers:
Researchers:
Sponsor: Fight for Sight
Publications
123 publications
Page 1 of 13
I. Christopher Lloyd, M. Edward Wilson, Rupal H. Trivedi, Susmito Biswas, Jane L. Ashworth, Elspeth Green, Jay Self, Kelly Voltz, Cyril Archambault, Thaddeus S. McClatchey, Scott K. McClatchey, Joanne Randeree, Jessica Gowing, Sophie Cowen, Lucy Barker, Ramesh Kekunnaya & Scott R. Lambert,
2025, Asia-Pacific Journal of Ophthalmology, 14(4)
Type: review
Savannah A. Lynn, Sudha Priya Soundara Pandi, Aida Sanchez‑Bretano, Anna Marie Muir, Lidia Parker, David S. Chatelet, Tutte Newall, Jennifer A. Scott, Eloise Keeling, Neil R. Smyth, Jay E. Self, Andrew J. Lotery, Helena Lee & J. Arjuna Ratnayaka,
2025, Alzheimer's Research & Therapy, 17(1)
Type: article
J. Arjuna Ratnayaka, Savannah A. Lynn, Sudha Priya Soundara Pandi, Aida Sanchez-Bretano, Anna Marie Muir, Lidia Parker, David S. Chatelet, Tutte Newall, Eloise Keeling, Neil R. Smyth, James E. Self, Helena Lee, Andrew J. Lotery & Jenny A. Scott,
2025, Investigative Ophthalmology & Visual Science, 66(8)
Type: conference
Eloise Keeling, Perry Carter, Abdi Malik Musa, Fatima Shawkat, Helena Lee & Jay E. Self,
2025, Diagnostics, 15(11)
Type: article
Daniel Osborne, Maddison McGowen, Jeremy Bradshaw, Helen Ellis, Megan Evans, James Stallwood, Joerg Fliege & Jay Self,
2025, British and Irish Orthoptic Journal, 21(1), 59-65
DOI: 10.22599/bioj.404
Type: article
Daniel Osborne, Jeremy Bradshaw, Maddison McGowan, Helen Ellis, Megan J.E. Evans, James Stallwood, Joerg Fliege & Jay E. Self,
2025, British and Irish Orthoptic Journal
Type: article
Steffen Bayer, Daniel Garillo, Marion Penn, Maria (Mary) Chorozoglou, Sally Brailsford, Eloise Keeling, Fatima Shawkat, Perry Carter, Helena Lee & Jay E. Self,
2025, BMC Health Services Research, 25(1)
Type: article
Cathy Williams, Anna Pease, Trudy Goodenough & Jay Self,
2025, Pilot and Feasibility Studies, 11(1)
Type: article
Anand E. Rajesh, Abraham Olvera-Barrios, Alasdair N. Warwick, Yue Wu, Kelsey V. Stuart, Mahantesh I. Biradar, Chuin Ying Ung, Anthony P. Khawaja, Robert Luben, Paul J. Foster, Charles R. Cleland, William U. Makupa, Alastair K. Denniston, Matthew J. Burton, Andrew Bastawrous, Pearse A. Keane, Mark A. Chia, Angus W. Turner, Cecilia S. Lee, Adnan Tufail, Aaron Y. Lee, Catherine Egan, Jay Self, Andrew Lotery, Jane Gibson, Sarah Ennis & Roxana Carare,
2025, Nature Communications, 16(1)
Type: article
Panagiotis I. Sergouniotis, Adam Diakite, Kumar Gaurav, Ewan Birney, Tomas Fitzgerald, Roxana Carare, Sarah Ennis, Jane Gibson, Andrew Lotery, James Morgan, Jay Self, Irene Stratton & et al,
2024, Bioinformatics, 41(1)
Type: article
Teaching
2018-2023 – Academic supervision for 5 PhD students across 2 institutions and external examiner for 3 PhD vivas. I have additionally mentored a junior Orthoptist through NIHR academic training culminating in him being the first AHP awarded a prestigious GW4 WELLCOME PhD studentship in 2022. I am therefore supporting the next generation of researchers and ensuring their work has real clinical impact.
External roles and responsibilities
Name:
Genomics in Ophthalmology: How genetic testing is redefining Ophthalmic disease
Role:
Speaker
Year:
2017
Name:
Nystagmus in the Paediatric Ophthalmology clinic
Role:
Speaker
Year:
2017
Name:
Why Eyes are Amazing and how to be a scientist
Role:
Speaker
Year:
2017
Name:
RP Fighting Blindess (External organisation)
Role:
Chair
Year:
2017 - 2022
Name:
External grant reviewer for Great Ormond Street Hospital Charity
Role:
Participant
Year:
2017
Name:
Consultant for London City & East Research Ethics Committee
Role:
Participant
Year:
2017
Name:
NIHR masterclass in clinical trials at RCOphth London
Role:
Speaker
Year:
2017
Name:
UK BIOBANK Eye and Ear consortium (External organisation)
Role:
Chair
Year:
2017 - 2022
Name:
International Council of Ophthalmology (External organisation)
Role:
Chair
Year:
2017 - 2022
Name:
Macula Society Road show
Role:
Speaker
Year:
2016
Name:
PhD thesis examiner
Role:
Examiner
Year:
2018
Name:
British Oculo-Motor Group Meeting (BOMG)
Role:
Speaker
Year:
2017
Name:
Member of UHS Hospital Charitable Funds Committee
Role:
Participant
Year:
2016
Name:
Pint of Science Invited Speaker
Role:
Speaker
Year:
2017
Name:
Invited medical advisor to Aniridia Network UK
Role:
Participant
Year:
2016
Name:
Research Advisory Panel member for INvision charity
Role:
Participant
Year:
2015
Name:
Nystagmus Network National Conference and open day
Role:
Speaker
Year:
2017
Name:
Albinism Fellowship 3 day Conference
Role:
Speaker
Year:
2017
Name:
The World Society of Paediatric Ophthalmology and Strabismus (WSPOS) Meeting
Role:
Speaker
Year:
2017
Name:
Roper Hall Alumni meeting Birmingham
Role:
Speaker
Year:
2017
Name:
Trends in Ophthalmology Meeting at the Royal Society
Role:
Speaker
Year:
2018
Name:
The Association for Research in Vision and Ophthalmology Mediator
Role:
Participant
Year:
2018
Name:
Royal College of Ophthalmologists (RCOphth) Congress - Two invited talks
Role:
Speaker
Year:
2018
Name:
Nystagmus Network Researchers Workshop
Role:
Speaker
Year:
2018
Name:
Nystagmus Awareness Day
Role:
Speaker
Year:
2018
Name:
EYESOC undergraduate evening meeting
Role:
Speaker
Year:
2018
Name:
Invited editor and reviewer of Cochrane review submission
Role:
Consultant
Year:
2019
Name:
MD viva for UCL
Role:
Examiner
Year:
2019
Name:
Starter Grant for Clinical Lecturers - invited reviewer
Role:
Consultant
Year:
2019
Name:
PhD viva examiner for University of Cardiff
Role:
Examiner
Year:
2019
Name:
Advisor and Consultant for theatre company
Role:
Consultant
Year:
2019
Name:
Paediatric Eye Research
Role:
Speaker
Year:
2019
Name:
Personalised Medicine In Ophthalmology
Role:
Speaker
Year:
2019
Name:
NHSE Commissioning review for Retinal Gene Therapy
Role:
Consultant
Year:
2019
Name:
PanelApp review for Genomics England
Role:
Consultant
Year:
2019
Name:
American nystagmus network workshop 2019
Role:
Speaker
Year:
2019
Name:
Research update for public open floor session
Role:
Speaker
Year:
2019
Name:
Public workshop on genetics
Role:
Speaker
Year:
2019
Name:
RCOphth Paediatric Ophthalmology Symposium
Role:
Speaker
Year:
2019
Name:
A new film from the David Katz foundation
Role:
Participant
Year:
2019
Name:
NIHR EME program reviewer
Role:
Consultant
Year:
2020
Name:
Southampton Research Biorespository Access Committee
Role:
Consultant
Year:
2020
Name:
NN online national meeting
Role:
Speaker
Year:
2020
Name:
Specialised Ophthalmology Service Specifications Review Group
Role:
Consultant
Year:
2020
Name:
Development of COVID19 mitigation guidelines for practice for BIOS
Role:
Consultant
Year:
2020
Name:
Online webinar - keynote speaker
Role:
Speaker
Year:
2020
Name:
Paediatric ophthalmology symposium
Role:
Speaker
Year:
2020
Name:
NN workshop invited session chair and speaker
Role:
Consultant
Year:
2020
Name:
NHS Genomic Medicine Service Alliance (GMSA) Research Collaborative Invited expert reviewer
Role:
Participant
Year:
2021
Name:
Recorded talk for careers events through Enterprise M3
Role:
Speaker
Year:
2021
Name:
Gift of Sight online event
Role:
Speaker
Year:
2021
Name:
RCOphth Congress 2021 - How to diagnose nystagmus
Role:
Speaker
Year:
2021
Name:
Beating Blindness
Role:
Keynote speaker
Year:
2021
Name:
Invited to Data Monitoring Committee for NIHR HTA project
Role:
Participant
Year:
2022
Name:
Nystagmus in Aniridia
Role:
Speaker
Year:
2021
Name:
Diagnosing Nystagmus - The UK experience
Role:
Speaker
Year:
2021
Name:
A diagnostic pathway for children with nystagmus
Role:
Speaker
Year:
2021
Name:
Royal Society of Medicine Genomic Ophthalmology: Diagnostics and therapeutics
Role:
Speaker
Year:
2021
Name:
CASK Gene Foundation UK website invited information pages
Role:
Consultant
Year:
2021
Name:
'Genetic Jargon' SIDESHOW article for the macular disease society
Role:
Participant
Year:
2013
Name:
British and Irish Orthoptic Society meeting
Role:
Speaker
Year:
2014
Name:
British and Irish Orthoptic Society
Role:
Speaker
Year:
2015
Name:
'Love your Garden' consultancy and interview regards blind patient
Role:
Consultant
Year:
2017
Name:
Nystagmus - Why is that eye moving?
Role:
Speaker
Year:
2017
Name:
Nominated for National Jack Kanski Award for Outstanding Ophthalmic Educator 2021
Role:
Participant
Year:
2021
Name:
Legal consultant for GBH case involving eye disease
Role:
Consultant
Year:
2015
Name:
Invited expert reviewer - NHS Genomic Medicine Service Alliance (GMSA) Research Collaborative
Role:
Consultant
Year:
2021
Name:
South West Peninsula Ophthalmology Regional Training Day Genomics in Ophthalmology
Role:
Speaker
Year:
2022
Name:
NIHR Data monitoring and ethics committee (DM(E)C) invited member for HTA study
Role:
Consultant
Year:
2021
Name:
Selector for BM5 and BM6 candidates for UoS
Role:
Participant
Year:
2022
Name:
Invited reviewer for NARF foundation PhD studentship applications
Role:
Participant
Year:
2022
Name:
Medical research Foundation / Moorfields Eye Charity
Role:
Consultant
Year:
2022
Name:
Nystagmus genetics - Why, when where and what?
Role:
Speaker
Year:
2023
Name:
Invited interviewer for UoS PCTA fellowships
Role:
Participant
Year:
2023
Name:
Centre for Health and Disability Assessments training program (DOWP) content review
Role:
Consultant
Year:
2023
Name:
Genomics in Ophthalmology - Midland Ophthalmological Society meeting 2023
Role:
Speaker
Year:
2023
Name:
Acadmic project supervision for FY2 doctor
Role:
Participant
Year:
2023
Name:
RETINA UK consultant
Role:
Consultant
Year:
2023
Name:
NIHR HTA IIH Intervention trial Data Monitoring Committee Meeting
Role:
Consultant
Year:
2022
Name:
NHS England - New Hospitals Program
Role:
Consultant
Year:
2023
Name:
iPhD - Phd Competence review examiner
Role:
Participant
Year:
2024
Name:
UCL PhD viva invited examiner
Role:
Examiner
Year:
2024
Name:
The big Nystagmus meetup
Role:
Speaker
Year:
2024
Name:
Medicine Networking Day
Role:
Participant
Year:
2024
Name:
'Ask the ophthalmologist' public open-floor meeting
Role:
Speaker
Year:
2024
Name:
National grant panel chair for Nystagmus Network
Role:
Consultant
Year:
2024
Name:
Progression review examiner
Role:
Examiner
Year:
2024
Name:
Invited keynote speaker for Johns Hopkins Zee lecture series
Role:
Speaker
Year:
2024
Name:
Invited clinical expert for Delphi process into XL-RP gene therapy
Role:
Consultant
Year:
2024
Name:
House of Lords reception hosted by lord Blunkett
Role:
Participant
Year:
2024
Name:
Heath Education England recruitment
Role:
Participant
Year:
2025
Name:
Southern Paediatric Regional Ophthalmology Group study day
Role:
Participant
Year:
2024
Name:
Invited panel member for PCTA interviews
Role:
Participant
Year:
2025
Name:
Expert content reviewer
Role:
Consultant
Year:
2025
Name:
American Nystagmus Network research conference (Philadelphia)
Role:
Speaker
Year:
2025
Name:
Nystagmus genomics session chair (for patients)
Role:
Speaker
Year:
2025
Name:
Guest editor for IOVA journal
Role:
Participant
Year:
2025
Name:
National Association of British Dispensing Opticians - Invited lecture
Role:
Speaker
Year:
2025
Name:
Ophthalmology NIPE lead for UHS
Role:
Participant
Year:
2025
Name:
BIPOSA conference invited speaker - Genomics for Ophthalmologists
Role:
Speaker
Year:
2025
Name:
Research as Applied to Medicine (RAM) lead for vision sciences
Role:
Participant
Year:
2025
Name:
Albinism Fellowship UK - National conference
Role:
Speaker
Year:
2025
Name:
Houses of Parliament APPG event hosted by Lord Blunkett
Role:
Participant
Year:
2025
Biography
Prizes
- Technology Advancement Award (2025)