Research
Research groups
Research interests
- Chemical Biology
- Medicinal Chemistry
- Protein Sciences
- Cancer
- Orphan and Rare Diseases
Current research
Our research is multidisciplinary and strongly relies on synthetic organic chemistry and biophysical techniques (e.g. DSF/DSC, ITC, NMR spectroscopy), combined with chemical/structural biology and computational methods (e.g. docking, QM). Our primary focus is on the development of chemistry driven approaches to modulate proteins’ physiological activity in a wide sense, with the ultimate goal to deliver new tools to study proteins’ function in living systems. Whenever possible, we exploit the knowledge gained from these studies to attempt tackling difficult problems in human health, notably in cancer, in collaboration with teams of biologists.
Research projects
Active projects
Researchers:
Completed projects
Researchers:
Sponsor: Royal Society
Researchers:
Sponsor: MSD Action Foundation
Researchers:
Sponsor: MSD Action Foundation