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Research project

Acellular/Smart Materials - 3D Architecture: UK RMP Hub

Project overview

The UKRMP2 Smart Materials Hub aims to develop the next generation of bioactive scaffolds and biomatrices to treat the eye, the musculoskeletal system and the liver. Regenerative medicine holds the promise of revolutionising patient care addressing the problems of an ageing population.

The Bone and Joint Research Group are part of the Acellular Smart Materials Hub with a specific focus on addressing skeletal repair and function moving from basic discovery science through to clinical translation. Research will seek to address the current unmet need for material systems that not only deliver cells safely but also provide cues for differentiation and the organisation of hierarchical and vascularised tissues. The development of materials with highly controlled spatio-temporal features that can respond to environmental triggers is also key in the quest for smarter more biomimetic solutions. The Acellular Smart materials UKRMP Programme will, over five years deliver innovative acellular material solutions to tissue regeneration with research encompassing fundamental research through to preclinical evaluation and, ultimately clinical delivery.

Staff

Lead researcher

Professor Richard Oreffo

Prof in Musculoskeletal Science
Other researchers

Professor Jon Dawson

Prof Fellow of Regenerative Medicine

Professor Nick Evans

Professor of Bioengineering

Collaborating research institutes, centres and groups

Research outputs

Daheui Choi,
Jiwoong Heo,
Juan Aviles Milan,
Jinkee Hong,
, 2021 , Materials Science and Engineering C , 118
Type: article
Benita, Scout MacKay,
Karen Marshall,
, 2021 , Biomedical Physics & Engineering Express , 7 (5)
Type: article
Katherine Anne Williams,
Joshua Steer,
& Philipp Schneider
, 2021 , Journal of Anatomy , 238 (3) , 653--668
Type: article
Miguel Xavier,
Maria-Eleni Kyriazi,
Stuart Lanham,
Konstantina Alexaki,
Elloise Matthews,
Tom Brown,
, 2021 , ACS Nano , 15 (4) , 6909--6916
Type: article
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