Dr Nicholas Evans is Associate Professor in Bioengineering with a joint appointment between the Faculty of Medicine and the Faculty of Engineering and Physical Sciences at the University of Southampton.
"My research focuses on stem cells, nanotechnology and how materials can be used to promote the regeneration of damaged or diseased tissues."
Nick was appointed as a lecturer in Bioengineering at Southampton University in January 2011. He holds a dual appointment between the Engineering and Physical Sciences and the Medicine, where he is based in the Centre for Human Development, Stem Cells and Regenerative Medicine.
He completed a PhD at King's College under the supervision of Prof John Pickup, where he researched techniques in fluorescence spectroscopy for tracking metabolism in cells by using their natural fluorescence. After experiencing some of the excitement of stem cell biology, he worked as an MRC postdoctoral fellow at Imperial College researching the effects of extracellular matrix on the differentiation of embryonic stem cells. He then took a postdoctoral position at Stanford University to study how a molecular pathway, called the Wnt signalling pathway, could be used to promote wound healing, before his appointment at Southampton.
He now leads a research team working on several aspects of regenerative medicine relating to bone and skin, and collaborates with a number of other researchers in the UK and Europe.
He teaches on the University’s Bachelor of Medicine and Masters of Engineering courses, and regularly explains his research to schools in the local area through the University’s outreach programmes and co-organises a residential workshop for school students on biomedical engineering with the Smallpeice Trust.
Nick has a personal website: www.evanslab.co.uk
Research in our labs focusses on regenerative medicine. Regenerative medicine is an area of scientific research that aims to develop drugs and technologies that replace or improve the function of organs or tissues. Often disease or injury leads to permanent damage to the body. In many cases this can lead to the need for transplanted tissue, which may be in short supply or simply not available.
By developing new nanomaterials, stem cells and new drugs, we hope to replace tissue, or to stimulate tissues to regenerate themselves. We are mainly interested in bone and skin repair.
We focus on two main areas of research – (1) nanomedicine and drug delivery and (2) mechanobiology. See www.evanslab.co.uk for more info
Current PhD Students
I am a fellow of the Higher Education Academy and lead an innovative programme of teaching, having established an entirely new multidisciplinary module in Southampton. In addition I teach on and administer the University’s Bachelor of Medicine, Masters of Engineering and MRes courses. I also have a keen interest in outreach – I organise a yearly residential workshop for school students on biomedical engineering with the Smallpeice Trust, and participate in a range of outreach programmes.
External roles and responsibilities
I am a pro-active and engaged academic with a world-leading research portfolio and an outward-facing and innovative attitude to teaching, administration and enterprise.
My research focusses on stem cells and biomaterials in tissue regeneration and development. I have held personal fellowships at Stanford University and at Imperial College. This experience led to my current focus on two main areas of research at the University of Southampton: drug delivery in bone repair and mechanobiology. My research is highly multidisciplinary, at the interface of the biological, medical, engineering and chemical sciences.
I have been awarded ~£2 M in grant income, and I have more than 4500 citations, >2000 of which are post-2016, with papers published in high impact and respected journals such as PNAS, Nature Materials and ACS Nano.
- Medical Research Council (UK) Career Development Fellowship (2008)