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Research project

Evaluating the impact of a molecular point-of-care test and treat strategy for influenza in hospitalised adults

Staff

Lead researchers

Professor Tristan Clark

Professor of Infectious Diseases
Connect with Tristan

Email: T.W.Clark@soton.ac.uk

Other researchers

Dr Sean Ewings

Associate Professor Head of Statistics
Connect with Sean

Email: sean.ewings@soton.ac.uk

Professor Joanne Lord

Director of SHTAC
Research interests
  • Joanne has research interests in health economic evaluation and decision modelling.
  • She has worked on a wide range of applied cost-effectiveness studies, including:
  • a review of newborn screening for inborn errors of metabolism;trials of diagnosis, patient education, structured decision-making and therapeutic interventions for arthritis and back pain;evaluations of diagnostic tests, preventive treatment and contact tracing for tuberculosis;a model of geographic allocation of resources for control of Chagas disease in Central America; andanalyses relating to the prevention and treatment of cardiovascular diseases. Her methodological contributions include an MRC funded project on whole pathway modelling for NICE clinical guidelines and an economic perspective on test evaluation. She has also contributed to health outcome and quality of life studies.
Connect with Joanne

Email: J.Lord@soton.ac.uk

Collaborating research institutes, centres and groups

Research outputs

Clinical characteristics, symptoms and outcomes of 1054 adults presenting to hospital with suspected COVID-19: a comparison of patients with and without SARS-CoV-2 infection
Nathan Brendish, Stephen Poole, Vasanth Naidu, Christopher Mansbridge, Nicholas Norton, Florina Borca, Hang Thi Thu Phan, Helen Wheeler, Matthew Harvey, Laura Presland & Tristan Clark, 2020, Journal of Infection, 81(6), 937-943
DOI: 10.1016/j.jinf.2020.09.033
Type: article
Clinical impact of molecular point-of-care testing for suspected COVID-19 in hospital: a prospective, interventional, non-randomised, controlled study (COV-19POC)
Nathan Brendish, Stephen Poole, Vasanth Naidu, Christopher Mansbridge, Nicholas Norton, Helen Wheeler, Laura Presland, Stephen Kidd, Nicholas Cortes, Florina Borca, Hang Phan, Gavin Babbage, Benoit Visseaux, Sean Ewings & Tristan Clark, 2020, The Lancet Respiratory Medicine, 8(12), 1192-1200
DOI: 10.1016/S2213-2600(20)30454-9
Type: article
Physical distancing in schools for SARS-CoV-2 and the resurgence of rhinovirus
Stephen Poole, Nathan Brendish, Alex Tanner & Tristan Clark, 2020, The Lancet Respiratory Medicine, 8(12), e92-e93
DOI: 10.1016/S2213-2600(20)30502-6
Type: letterEditorial
SARS-CoV-2 has displaced other seasonal respiratory viruses: results from a prospective cohort study
Stephen Poole, Nathan Brendish & Tristan Clark, 2020, Journal of Infection, 81(6), 966-972
DOI: 10.1016/j.jinf.2020.11.010
Type: article
Diagnostic accuracy of the FebriDx host response point-of-care test in patients hospitalised with suspected COVID-19
Tristan Clark, Nathan Brendish, Stephen Poole, Vasanth Naidu, Christopher Mansbridge, Nicholas Norton, Helen Wheeler, Laura Presland & Sean Ewings, 2020, Journal of Infection, 81(4), 607-613
DOI: 10.1016/j.jinf.2020.06.051
Type: article
Inflammatory phenotyping predicts clinical outcome in COVID-19
H Burke, A Freeman, D C Cellura, B L Stuart, N J Brendish, S Poole, F Borca, H T T Phan, N Sheard, S Williams, C M Spalluto, K J Staples, T W Clark & T M A Wilkinson, 2020, Respiratory Research, 21(1), 245
DOI: 10.1186/s12931-020-01511-z
Type: article
Integrating molecular point-of-care testing for influenza into primary care: a mixed-methods feasibility study
Tristan Clark, Simon de Lusignan, Uy Hoang, Harshana Liyanage, Manasa Tripathy, Ivelina Yonova, Rachel Byford, Filipa Ferreira & Javier Diez-Domingo, 2020, The British journal of general practice : the journal of the Royal College of General Practitioners, 70(697), 555-562
DOI: 10.3399/bjgp20X710897
Type: article