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Research project

Evaluating the impact of a molecular point-of-care test and treat strategy for influenza in hospitalised adults

Staff

Lead researchers

Professor Tristan Clark

Professor of Infectious Diseases
Connect with Tristan

Email: T.W.Clark@soton.ac.uk

Other researchers

Dr Sean Ewings

Associate Professor Head of Statistics
Connect with Sean

Email: sean.ewings@soton.ac.uk

Professor Joanne Lord

Director of SHTAC
Research interests
  • Joanne has research interests in health economic evaluation and decision modelling.
  • She has worked on a wide range of applied cost-effectiveness studies, including:
  • a review of newborn screening for inborn errors of metabolism;trials of diagnosis, patient education, structured decision-making and therapeutic interventions for arthritis and back pain;evaluations of diagnostic tests, preventive treatment and contact tracing for tuberculosis;a model of geographic allocation of resources for control of Chagas disease in Central America; andanalyses relating to the prevention and treatment of cardiovascular diseases. Her methodological contributions include an MRC funded project on whole pathway modelling for NICE clinical guidelines and an economic perspective on test evaluation. She has also contributed to health outcome and quality of life studies.
Connect with Joanne

Email: J.Lord@soton.ac.uk

Collaborating research institutes, centres and groups

Research outputs

Routine molecular point-of-care testing for SARS-CoV-2 reduces hospital-acquired COVID-19
Robert Livingstone, Hlaing Lin, Nathan Brendish, Stephen Poole, Florina Borca, Alex Tanner, Trevor Smith , Matt Stammers & Tristan Clark, 2022, Journal of Infection, 84(4), 558-565
DOI: 10.1016/j.jinf.2022.01.034
Type: article
Rapid syndromic PCR testing in patients with respiratory tract infections reduces time to results and improves microbial yield
Tristan Clark, S Serigstat, D Markussen, Harleen Grewal, M Ebbesen, O Kommedal, L Heggelund, CH van Werkhoven, D Faurholt-Jepsen, C Ritz, E Ulvestad, R Bjorneklett & ST Knoop, 2022, Scientific Reports, 12(326)
DOI: 10.1038/s41598-021-03741-7
Type: article
A SARS-CoV-2 nucleocapsid ELISA represents a low-cost alternative to lateral flow testing for community screening in LMI countries
Maria Humbert, Precious Opurum, Nathan Brendish, Stephen Poole, Peijun He, Ioannis Katis, Jerry Quaye, Yaw Bediako, Patrick Duriez, R.W. Eason, Collin Sones, Osbourne Quaye, Gordon Awandare, Myron Christodoulides, Tristan Clark, Peter Quashie & Christopher Mccormick, 2022, Journal of Infection, 84(1), 48-55
DOI: 10.1016/j.jinf.2021.08.049
Type: article
Comparison of rapid molecular testing methods for detecting respiratory viruses in emergency care: a prospective study
Tristan Clark, Dagfinn Markussen, Harleen Grewal, Siri T Knoop, Sondre Serigstad, Oyvind Kommedal, Marit Ebbeseb, Elling Ulvestad, Rune O. Bjørneklett & CAPNOR study group CAPNOR study group, 2021, Infectious Diseases, 54(4), 247
DOI: 10.1080/23744235.2021.2003857
Type: article
Increase in circulation of non-SARS-CoV-2 respiratory viruses following easing of social distancing is associated with increasing hospital attendance
Alex R. Tanner, Nathan J. Brendish, Stephen Poole, Jessica Pregon & Tristan W. Clark, 2021, Journal of Infection, 83(4), 496-522
DOI: 10.1016/j.jinf.2021.07.022
Type: letterEditorial
SARS-CoV-2 Viral load at presentation to hospital is independently associated with the risk of death
Alex Tanner, Hang Thi Thu Phan, Nathan Brendish, Florina Borca, Kate Beard, Stephen Poole & Tristan Clark, 2021, Journal of Infection, 83(4), 458-466
DOI: 10.1016/j.jinf.2021.08.003
Type: article
Accuracy of rapid point-of-care antibody test in patients with suspected or confirmed COVID-19
Rama Vancheeswaran, Merlin Luke Willcox, Beth Stuart, Matthew Knight, Hala Kandil, Andrew Barlow, Mayon Haresh Patel, Jade Stockham, Aisling O'Neill, Tristan W. Clark, Tom Wilkinson, Paul Little, Nick Francis, Gareth Griffiths & Michael Moore, 2021, Journal of Infection, 84(1), 94-118
DOI: 10.1016/j.jinf.2021.07.006
Type: letterEditorial